Browsing by Author "Zelenyak, Oresta"

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    Poly(ethylene glycol) and poly(propylene glycol)-containing aminofunctional copolyesters for biomedical application
    (Lviv Polytechnic Publishing House, 2016) Voronovska, Anna; Tovarnitskyi, Andrii; Zelenyak, Oresta; Ranevska, Myroslava; Stasiuk, Anna; Ferens, Mariia; Fihurka, Nataliia; Tarnavchyk, Ihor; Lviv Polytechnic National University; North Dakota State University
    Polyesters (pseudo-poly(amino acids) based on the dicarboxilic amino acids and diols of different molecular weight (polyethylene glycols with polycondensation degree of 2-8) were synthesized using N,N′-dicyclo-hexyl-carbodiimide (DCC) – the activator of carboxyl grous. Also were synthesized the novel amphiphilic polyesterethers based on natural dibasic amino acids including their N-derivatives with controllable colloidal properties and ionogenic groups of cationic type (amino groups). The complex of properties (amphiphilicity, biodegradability and non-toxic degradation of the products) and the ability to form self-assembled structures in aqueous environment allow to use such polymers to form in vivo delivery systems.