Вісники та науково-технічні збірники, журнали
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Item Optimization of oligonucleotides characteristics with topsis(Видавництво Львівської політехніки, 2023-02-28) Javanbakht, Taraneh; Concordia UniversityThis paper focused on a new application of the TOPSIS method for the prediction and optimization of the oligonucleotides characteristics. This method has been used for these purposes as it has shown its efficacy for these analyses. This is the first time that it has been applied to the investigation of these biomolecules. The hypothesis in this paper was that the characteristics of these biomaterials would be optimized according to their structural differences. The obtained results showed that the stabilization of oligonucleotides would affect their ranking with TOPSIS when the stability of these biomolecules increased against enzymes in their structure. In other words, the oligonucleotides with less enzymatic degradation were ranked better with this method. This study showed the first application of this algorithm for the prediction and optimization of the oligonucleotides’ characteristics. The results in this work revealed that the ranks of candidates depended on their distances from their ideal solutions. This showed that TOPSIS could be used as an appropriate method in the optimization of oligonucleotides as the rankings with this method would coincide with the data that concern the stability of these biomolecules against enzymatic degradation. The results of this work could be applied for the preparation of novel materials with applications in science and engineering.Item Optimization of physical instruments’ characteristics with topsis(Видавництво Львівської політехніки, 2022-02-22) Javanbakht, Taraneh; Concordia University; University of Quebec in MontrealThe present study focuses on the characteristics optimization of the physical instruments with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). The hypothesis in this research work was that the characteristics of spectrometers and rheometers could affect their rankings, which in turn could be influenced by the underestimation of their cost criterion. In this paper, the characteristics optimization of the FTIR spectrometers and rheometers was carried out with TOPSIS. Moreover, its modified algorithm was also used in order to analyze the inappropriate consideration of these instruments due to category confusion. The modification of TOPSIS helped obtain an automated decision-making method for the treatment of data. The results showed that the rankings of the FTIR spectrometers and rheometers were different as expected. Moreover, the rankings of the FTIR spectrometers were different with using the unmodified and modified TOPSIS; however, that of the rheometers did not change. The change in the ranking of the FTIR spectrometers was due to the application of the fuzzy disjunction in the TOPSIS code. In this case, the first and second candidates were placed in the first and second positions, respectively, whereas the second candidate had a better rank than the first one in the analysis with the unmodified TOPSIS code. The rank improvement of the first candidate in the category of FTIR spectrometers after the modification of the TOPSIS code was also observed. The results of this work can be used in mechanical engineering and materials science as the appropriate use of instruments in these fields depends on the consideration of their characteristics for which their optimization in comparison with those of other instruments could provide interesting results. Such investigations would provide complementary data for the experimental approaches in further applications.