Anthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity

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dc.citation.conference7th International youth science forum «Litteris et Artibus»
dc.citation.epage33
dc.citation.journalTitleLitteris et Artibus : матеріали
dc.citation.spage32
dc.contributor.affiliationLviv Polytechnic National University
dc.contributor.affiliationIstanbul University, TURKEY, Istanbul
dc.contributor.affiliationDivision of Analytical Chemistry, TURKEY, Istanbul
dc.contributor.affiliationDepartment of Mechanisms of Organic Reactions, UKRAINE, Kyiv
dc.contributor.authorKopak, Nazar
dc.contributor.authorStasevych, Maryna
dc.contributor.authorZvarych, Viktor
dc.contributor.authorDeniz, Nahide Gulsah
dc.contributor.authorSayil, Cigdem
dc.contributor.authorOzyurek, Mustafa
dc.contributor.authorGuclu, Kubilya
dc.contributor.authorVovk, Mykhailo
dc.contributor.authorNovikov, Volodymyr
dc.coverage.placenameЛьвів
dc.coverage.placenameLviv
dc.coverage.temporal23–25 листопада 2017 року
dc.coverage.temporal23–25 November, 2017
dc.date.accessioned2018-04-12T13:07:12Z
dc.date.available2018-04-12T13:07:12Z
dc.date.created2017-12-23
dc.date.issued2017-12-23
dc.description.abstractAn effective method for the synthesis of 1-anthraquinonyl hydrazones containing the acyl- and/or ethoxycarbonyl, carbo- and heterocyclic fragments in the ylidene moiety has been shown, which are convenient reagents for further chemical transformations. Investigation of the antioxidant activity of hydrazones has allowed to identify promising compounds that can be suggested for further research as antioxidant substances.
dc.format.extent32-33
dc.format.pages2
dc.identifier.citationAnthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity / Nazar Kopak, Maryna Stasevych, Viktor Zvarych, Nahide Gulsah Deniz, Cigdem Sayil, Mustafa Ozyurek, Kubilya Guclu, Mykhailo Vovk, Volodymyr Novikov // Litteris et Artibus : proceedings, 23–25 November, 2017. — Lviv : Lviv Polytechnic Publishing House, 2017. — P. 32–33. — (6th International academic conference «Chemistry & chemical technology 2017» (CCT-2017)).
dc.identifier.citationenAnthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity / Nazar Kopak, Maryna Stasevych, Viktor Zvarych, Nahide Gulsah Deniz, Cigdem Sayil, Mustafa Ozyurek, Kubilya Guclu, Mykhailo Vovk, Volodymyr Novikov // Litteris et Artibus : proceedings, 23–25 November, 2017. — Lviv : Lviv Polytechnic Publishing House, 2017. — P. 32–33. — (6th International academic conference «Chemistry & chemical technology 2017» (CCT-2017)).
dc.identifier.isbn978-966-941-108-2
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/40532
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Polytechnic Publishing House
dc.relation.ispartofLitteris et Artibus : матеріали, 2017
dc.relation.ispartofLitteris et Artibus : proceedings, 2017
dc.relation.references[1] N. Belskaya, W. Dehaen, V. Bakulev, “Synthesis and properties of hydrazones bearing amide, thioamide and amidine functions,” Arkivoc, vol. I, pp. 275-332, 2010.
dc.relation.references[2] R. Ali, A. Marella, T. Alam, R. Naz, M. Akhter, Md. Shaquiquzzaman, R. Saha, O. Tanwar, M. Alam, J. Hooda, “Review of biological activities of hydrazones,” Indones. J. Pharm., vol. 23, pp. 193-202, 2012.
dc.relation.references[3] Q.A. Acton, Ed., Anthraquinones. Advances in Research and Application. Atlanta : Scholarly Editions,2013.
dc.relation.references[4] S. Arai, S. Kato, M.B. Hida, “Anthraquinone pharmaceutical compounds and uses therefor,” J. Chem. Soc. Jpn., vol. 58, p. 1458, 1985.
dc.relation.references[5] I. Antonini, P. Polucci, D. Cola, G. Palmieri, S. Martelli, M. Bon-temps-Gracz, “Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs,” Farmaco, vol. 48, pp. 1641-1648, 1993.
dc.relation.references[6] V.A. Loskutov, “Reaction of anthrone and its 1-and 4- substituted derivatives with sulfur in the presence of nucleophiles,” Russ. J. Org. Chem., vol. 36, pp. 1478-1481, 2000.
dc.relation.references[7] M. Regitz, “Reaktionen aktiver Methylen-verbindungen mit Aziden, III. Über die Diazo-, Azino- und Triphenylphosphazino-Derivate des Anthrons und Thioxanthen-S-dioxids,” Chem. Ber., vol. 97, pp. 2742-2754, 1964.
dc.relation.references[8] S.L. Vorob’eva, V.N. Buyanov, I.I. Levina, N.N. Suvorov, “Naphthindoles. 2. Naphtho[2,3-e]indole-4,9- diones and naphtho[2,3-f]indole-5,10-diones,” Chem. Heterocycl. Compd., vol. 25, pp. 646–649, 1989.
dc.relation.references[9] K. MeeKyoung, D.F. Wiemer, “EDC-mediated condensations of 1-chloro-5-hydrazino-9, 10-anthracenedione,1-hydrazino-9,10-anthracenedione, and the corresponding anthrapyrazoles,” Tetrahedron Lett., vol. 45,pp. 4977- 4980, 2004.
dc.relation.references[10]V. Zvarych, M. Stasevych, V. Lunin, N.G. Deniz, C. Sayil, M. Ozyurek, K. Guclu, M. Vovk, V. Novikov, “Synthesis and investigation of antioxidant activity of the dithiocarbamate derivatives of 9,10-anthracenedione”, Monatsh. Chem., vol. 147, pp. 2093-2101,2016.
dc.relation.references[11]R. Apak, K. Güçlü, M. Özyürek, S.E. Karademir, “Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method,” J. Agric. Food Chem., vol.52,pp.7970-7981, 2004.
dc.relation.references[12]B. Bekdeşer, M. Özyürek, K. Güçlü, F. Üstün Alkan, R. Apak,“Development of a new catalase activity assay for biological samples using optical CUPRAC sensor,” Spectrochim. Acta Part A, vol. 132, pp. 485-490, 2014.
dc.relation.referencesen[1] N. Belskaya, W. Dehaen, V. Bakulev, "Synthesis and properties of hydrazones bearing amide, thioamide and amidine functions," Arkivoc, vol. I, pp. 275-332, 2010.
dc.relation.referencesen[2] R. Ali, A. Marella, T. Alam, R. Naz, M. Akhter, Md. Shaquiquzzaman, R. Saha, O. Tanwar, M. Alam, J. Hooda, "Review of biological activities of hydrazones," Indones. J. Pharm., vol. 23, pp. 193-202, 2012.
dc.relation.referencesen[3] Q.A. Acton, Ed., Anthraquinones. Advances in Research and Application. Atlanta : Scholarly Editions,2013.
dc.relation.referencesen[4] S. Arai, S. Kato, M.B. Hida, "Anthraquinone pharmaceutical compounds and uses therefor," J. Chem. Soc. Jpn., vol. 58, p. 1458, 1985.
dc.relation.referencesen[5] I. Antonini, P. Polucci, D. Cola, G. Palmieri, S. Martelli, M. Bon-temps-Gracz, "Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs," Farmaco, vol. 48, pp. 1641-1648, 1993.
dc.relation.referencesen[6] V.A. Loskutov, "Reaction of anthrone and its 1-and 4- substituted derivatives with sulfur in the presence of nucleophiles," Russ. J. Org. Chem., vol. 36, pp. 1478-1481, 2000.
dc.relation.referencesen[7] M. Regitz, "Reaktionen aktiver Methylen-verbindungen mit Aziden, III. Über die Diazo-, Azino- und Triphenylphosphazino-Derivate des Anthrons und Thioxanthen-S-dioxids," Chem. Ber., vol. 97, pp. 2742-2754, 1964.
dc.relation.referencesen[8] S.L. Vorob’eva, V.N. Buyanov, I.I. Levina, N.N. Suvorov, "Naphthindoles. 2. Naphtho[2,3-e]indole-4,9- diones and naphtho[2,3-f]indole-5,10-diones," Chem. Heterocycl. Compd., vol. 25, pp. 646–649, 1989.
dc.relation.referencesen[9] K. MeeKyoung, D.F. Wiemer, "EDC-mediated condensations of 1-chloro-5-hydrazino-9, 10-anthracenedione,1-hydrazino-9,10-anthracenedione, and the corresponding anthrapyrazoles," Tetrahedron Lett., vol. 45,pp. 4977- 4980, 2004.
dc.relation.referencesen[10]V. Zvarych, M. Stasevych, V. Lunin, N.G. Deniz, C. Sayil, M. Ozyurek, K. Guclu, M. Vovk, V. Novikov, "Synthesis and investigation of antioxidant activity of the dithiocarbamate derivatives of 9,10-anthracenedione", Monatsh. Chem., vol. 147, pp. 2093-2101,2016.
dc.relation.referencesen[11]R. Apak, K. Güçlü, M. Özyürek, S.E. Karademir, "Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method," J. Agric. Food Chem., vol.52,pp.7970-7981, 2004.
dc.relation.referencesen[12]B. Bekdeşer, M. Özyürek, K. Güçlü, F. Üstün Alkan, R. Apak,"Development of a new catalase activity assay for biological samples using optical CUPRAC sensor," Spectrochim. Acta Part A, vol. 132, pp. 485-490, 2014.
dc.rights.holder© Національний університет “Львівська політехніка”, 2017
dc.subject9 10-anthraquinone
dc.subjectdiazonium salt
dc.subjecthydrazone
dc.subjectα-active ketones
dc.subjectβ-carbonylcontaining compunds
dc.subjectantioxidant activity
dc.titleAnthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity
dc.typeConference Abstract

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