New heterocyclic scaffolds with thiophene and 1,2,4-triazole rings

Date

2017-12-23

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Видавництво Львівської політехніки
Lviv Polytechnic Publishing House

Abstract

Some chemical modifications of the Gewald 2- amino-thiophenes and 3-aminothiophenes were established. A number of new substituted thienotriazolopyrimidines, thienotriazoles and thiophenyl-triazolothiadiazine were obtained. This study provides new approaches to the construction of substituted 1H-1,2,4-triazoles bearing thiophene core and allows to use data in medical chemistry for further drug discover.

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Keywords

2-aminothiophene, 3-aminothiophene, 1 2 4- triazoles, aminohydrazones, thienotriazolopyrimidines, triazolothiadiazines

Citation

New heterocyclic scaffolds with thiophene and 1,2,4-triazole rings / Mykola Tupychak, Olga Shyyka, Nazariy Pokhodylo, Mykola Obushak // Litteris et Artibus : proceedings, 23–25 November, 2017. — Lviv : Lviv Polytechnic Publishing House, 2017. — P. 56–57. — (6th International academic conference «Chemistry & chemical technology 2017» (CCT-2017)).

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