Effect of diesel-emitted nanostructured particles on the apparent surface rheology of model lung surfactant

dc.citation.conferenceLitteris et Artibus
dc.contributor.affiliationWarsaw University of Technologyuk_UA
dc.contributor.authorSosnowski, Tomasz R.
dc.contributor.authorPenconek, Agata
dc.contributor.authorJabłczyńska, Katarzyna
dc.coverage.countryUAuk_UA
dc.coverage.placenameLvivuk_UA
dc.date.accessioned2018-05-10T08:18:19Z
dc.date.available2018-05-10T08:18:19Z
dc.date.issued2016
dc.description.abstractDiesel exhaust contain nanostructured particles which may be inhaled and may interact with the lung surfactant (LS) present in the respiratory system. This work reports the experimental analysis of surface tension variations in model LS system which contain diesel exhaust particles (DEPs). Experiments of oscillatory deformations of air/liquid interface under physiological-like conditions allowed to determine the changes in apparent surface rheological parameters, which indicated evident alteration of mechanical properties of LS caused by DEPs. These results allow to speculate on possible adverse effects of inhaled DEPs on LS in vivo.uk_UA
dc.format.pages446-448
dc.identifier.citationSosnowski Tomasz R. Effect of diesel-emitted nanostructured particles on the apparent surface rheology of model lung surfactant / Tomasz R. Sosnowski, Agata Penconek, Katarzyna Jabłczyńska // Litteris et Artibus : proceedings of the 6th International youth science forum, November 24–26, 2016, Lviv, Ukraine / Lviv Polytechnic National University. – Lviv : Lviv Polytechnic Publishing House, 2016. – P. 446–448. – Bibliography: 10 titles.uk_UA
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/41049
dc.language.isoenuk_UA
dc.publisherLviv Polytechnic Publishing Houseuk_UA
dc.relation.referencesen[1] D.B. Kittelson, "Engines and nanoparticles: A review", J. Aerosol Sci. vol. 29, pp. 575-588, 1998. [2] A. Penconek, B. Zgiet, T.R. Sosnowski, A. Moskal, "Filtering of DEP (Diesel Exhaust Particles) in fibrous filters", Chem. Eng. Trans. vol. 32, pp. 1987-1992, 2013. [3] C.A. Pope 3rd, et al. "Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution", JAMA vol, 287, pp. 1132–1141, 2002. [4] T.R. Sosnowski, "Nanosized and nanostructured particles in pulmonary drug delivery", J. Nanosci. Nanotechnol. vol.15, pp. 3476-3487, 2015. [5] T.R. Sosnowski, L. Gradoń, A. Podgórski, "Influence of insoluble aerosol deposits on the surface activity of the pulmonary surfactant: a possible mechanism of alveolar clearance retardation", Aerosol Sci. Technol. vol. 32, pp. 52-60, 2000. [6] K. Kramek-Romanowska, M. Odziomek, T.R. Sosnowski, "Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air–water interface", Colloids and Surfaces A: Physicochem. Eng. Aspects vol. 480, pp. 149-158, 2015. [7] D. Kondej, T.R. Sosnowski, "Effect of clay nanoparticles on model lung surfactant: a potential marker of hazard from nanoaerosol inhalation", Envir. Sci. Pollution Res. vol. 23, pp. 4660-4669, 2016. [8] A. Penconek, A. Drążyk, A. Moskal, "Penetration of Diesel Exhaust Particles through commercially available dust half masks", Ann. Occup. Hyg. vol. 57, pp. 360-373, 2012. [9] H. Burtscher, "Physical characterization of particulate emissions from diesel engines: a review", J. Aerosol Sci. vol. 36, pp. 896–932, 2005. [10] J. Lyklema, "Fundamentals of interface and colloid science", Vol.3., Academic Press, London, 2000.uk_UA
dc.subjectnanostructured aerosol particlesuk_UA
dc.subjectdiesel exhaustuk_UA
dc.subjectlung surfactantuk_UA
dc.subjectsurface rheologyuk_UA
dc.subjecthealth effectsuk_UA
dc.titleEffect of diesel-emitted nanostructured particles on the apparent surface rheology of model lung surfactantuk_UA
dc.typeConference Abstractuk_UA

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