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Item New heterocyclic scaffolds with thiophene and 1,2,4-triazole rings(Видавництво Львівської політехніки, 2017-12-23) Tupychak, Mykola; Shyyka, Olga; Pokhodylo, Nazariy; Obushak, Mykola; Ivan Franko National University of LvivSome chemical modifications of the Gewald 2- amino-thiophenes and 3-aminothiophenes were established. A number of new substituted thienotriazolopyrimidines, thienotriazoles and thiophenyl-triazolothiadiazine were obtained. This study provides new approaches to the construction of substituted 1H-1,2,4-triazoles bearing thiophene core and allows to use data in medical chemistry for further drug discover.