Chemistry & Chemical Technology. – 2015. – Vol. 9, No. 2

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It is the scientific-technical journal in English in Ukraine discussing actual problems of chemistry and chemical technology. Compared with other chemical journals Ch&ChT is publishing materials of both theoretical and practical values in such fields as analytical, general organic, physical and inorganic chemistry; chemistry of high molecular compounds; materials science and engineering; chemical kinetics and catalysis; technology of inorganic substances; technology of organic synthesis products; chemical technology of processing of combustible minerals; processes and apparatus of chemical and food productions; biotechnology and ecology.

Chemistry & Chemical Technology : [the scientific-technical journal] / Lviv Polytechnic National University ; editor-in-chief M. Bratychak. – Lviv : Publishing House of Lviv Polytechnic National University, 2015. – Volume 9, number 2. – P. 131–260, V : ill.

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    High performance liquid chromatographic determination of bupropion using H-clinoptilolite as a sorbent for plasma and urine purification
    (Publishing House of Lviv Polytechnic National University, 2015) Halkevych, Iryna; Ivanauskas, Liudas; Bidnychenko, Yuriy; Barsteigiene, Zita
    The coupling of solid-phase extraction (SPE) using H-clinoptilolite as an adsorbent with a high performance liquid chromatography (HPLC) method was developed for the high efficiency enrichment and rapid determination of bupropion in plasma and urine. The effect of the adsorbent particles size and pH on adsorption behavior of bupropion to H-clinoptilolite was evaluated. The experimental conditions of the sorbent preparation were developed, the effective solvents for the sorbent conditioning were chosen. The optimal eluent for bupropion extraction by H-clinoptilolite was chosen. Вивчена ефективність застосування Н-клиноптилоліту як адсорбенту для твердофазної екстракції (ТФЕ) бупропіону з плазми та сечі з використанням високоефективної рідинної хроматографії (ВЕРХ). Досліджено залежність сорбції бупропіону Н-клиноптилолітом від розміру зерен фракції та рН середовища. Розроблено умови підготовки сорбенту, підібрано розчинники для кондиціонування сорбенту, а також підібрано оптимальний елюент для екстракції бупропіону з Н-клиноптилоліту.