Synthesis of new heterocyclic compounds based on 1,4-naphthoquinones and azomethines of α-amino acids

Simple item page
dc.contributor.authorKudrinetska, Anastasiia
dc.contributor.authorShakh, Yurii
dc.contributor.authorBolibrukh, Khrystyna
dc.contributor.authorKarkhut, Andrii
dc.contributor.authorLytvyn, Bohdan
dc.contributor.authorPolovkovych, Sviatoslav
dc.date.accessioned2015-04-17T11:39:15Z
dc.date.available2015-04-17T11:39:15Z
dc.date.issued2013
dc.description.abstractAnalysed the literature sources to establish the basic ˝skafolds ˝, necessary for the design of "drugs-like molecules." Created the combinatorial library of new heterocyclic derivatives of 1,4-naphthoquinone. A docking study for determining structure leaders was conducted, ways of optimization the chemical structures to enhance the biological activity were determined. Designed by methods of obtaining a new heterocyclic derivatives based on 1,4-naphthoquinone and conducted search including effective anti-cancer agents.uk_UA
dc.identifier.citationSynthesis of new heterocyclic compounds based on 1,4-naphthoquinones and azomethines of α-amino acids / Anastasiia Kudrinetska, Yurii Shakh, Khrystyna Bolibrukh, Andrii Karkhut, Bohdan Lytvyn, Sviatoslav Polovkovych // Хімія та хімічні технології : матеріали IІI Міжнародної конференції молодих вчених CCT-2013, 21–23 листопада 2013 року, Україна, Львів / Національний університет "Львівська політехніка". – Львів : Видавництво Львівської політехніки, 2013. – С. 106–107. – (4-й Міжнародний молодіжний фестиваль науки "Litteris et Artibus"). – Bibliography: 16 titles.uk_UA
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/26998
dc.language.isoenuk_UA
dc.publisherВидавництво Львівської політехнікиuk_UA
dc.subjectheterocyclic compoundsuk_UA
dc.subject1,4-naphthoquinonesuk_UA
dc.subjectazomethines of α-amino acidsuk_UA
dc.subjectanticancer agentsuk_UA
dc.subject"drug-like" compoundsuk_UA
dc.subject1,3-dypolar cycloaddition reactionuk_UA
dc.titleSynthesis of new heterocyclic compounds based on 1,4-naphthoquinones and azomethines of α-amino acidsuk_UA
dc.typeArticleuk_UA

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
039-106-107.pdf
Size:
267.29 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Хімія та хімічні технології (CCT-2013). – 2013 р.