Research of antioxidant properties of grape marc extracts as perspective pharmaceutical and cosmetic products

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dc.citation.epage85
dc.citation.issue2
dc.citation.spage79
dc.contributor.affiliationНаціональний університет “Львівська політехніка”
dc.contributor.affiliationLviv Polytechnic National University
dc.contributor.authorСкіра, А. Р.
dc.contributor.authorЯремкевич, О. С.
dc.contributor.authorЗаярнюк, Н. Л.
dc.contributor.authorКурка, М. С.
dc.contributor.authorSkira, A. R.
dc.contributor.authorIaremkevych, O. S.
dc.contributor.authorZayarnyuk, N. L.
dc.contributor.authorKurka, M. S.
dc.coverage.placenameЛьвів
dc.coverage.placenameLviv
dc.date.accessioned2024-01-22T07:35:23Z
dc.date.available2024-01-22T07:35:23Z
dc.date.created2020-03-16
dc.date.issued2020-03-16
dc.description.abstractДосліджено антиоксидантну активність (АА) різних екстрактів виноградних пожитків (Vitis vinifera L.). Радикальну абсорбційну активність (RAA) обчислювали в реакціях з радикалами DPPH та ABTS•+ та AA у гомогенаті печінки щурів за двома маркерами окисного стресу: вмістом тіобар- бітуративних продуктів та карбонільними групами білків. Всі екстракти виявляли антиоксидантну активність. Екстракт на водній основі та 96 % етаноловий екстракт, одержаний методом теплової ванни, були інгібіторами утворення вільнорадикального окислення ліпідів та білків. 96 % етаноловий екстракт є перспективним для розроблення фармацевтичних та косметичних продуктів.
dc.description.abstractThe antioxidant activity (AA) of various extracts of grape marc (Vitis vinifera L.) was studied. Radical absorption activity (RAA) was calculated in reactions with DPPH+ and ABTS•+radicals and AA in rat liver homogenate by two markers of oxidative stress (OS): contents of thiobarbiturative products and carbonyl groups of proteins. All the extracts showed antioxidant activity. Water-based extract and 96 % ethanol extract obtained via heat bath method were inhibitors of the formation of free radical oxidation of lipids and proteins. 96% ethanol extract is promising for the development of pharmaceutical and cosmetic products.
dc.format.extent79-85
dc.format.pages7
dc.identifier.citationResearch of antioxidant properties of grape marc extracts as perspective pharmaceutical and cosmetic products / A. R. Skira, O. S. Iaremkevych, N. L. Zayarnyuk, M. S. Kurka // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2020. — Vol 3. — No 2. — P. 79–85.
dc.identifier.citationenResearch of antioxidant properties of grape marc extracts as perspective pharmaceutical and cosmetic products / A. R. Skira, O. S. Iaremkevych, N. L. Zayarnyuk, M. S. Kurka // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2020. — Vol 3. — No 2. — P. 79–85.
dc.identifier.doidoi.org/10.23939/ctas2020.02.079
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/60810
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofChemistry, Technology and Application of Substances, 2 (3), 2020
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dc.relation.referencesen1. Muhlack, R. A., Potumarthi, R., Jeffery, D. W.(2018), Sustainable Wineries Through Waste Valorisation: A Review of Grape Marc Utilisation for Value-Added Products. Waste Management, 72, 99–118. https://doi.org/10.1016/j.wasman.2017.11.011
dc.relation.referencesen2. Gollücke, A. P., Ribeiro, D. A.. (2012) Use of grape polyphenols for promoting human health: a review of patents. Recent Pat Food Nutr Agric. 4(1), 26–30.
dc.relation.referencesen3. Gollücke, A. P. (2010) Recent applications of grape polyphenols in foods, beverages and supplements. Recent patents on food, nutrition & agriculture, 2(2), 105–9.
dc.relation.referencesen4. Dwyer, K., Hosseinian, F., Rod, M. R. (2014) The Market Potential ofGrapeWaste Alternatives. Journal of Food Research, 3(2), 91–106. http://dx.doi.org/10.5539/jfr.v3n2p91
dc.relation.referencesen5. Pooja Doshi, Pandurang Adsule, Kaushik Banerjee, Dasharath Oulkar. (2015). Phenolic compounds, antioxidant activity and insulinotropic effect of extracts prepared from grape (Vitis vinifera L) byproducts. Journal of Food Science and Technology, 52, 181–190.
dc.relation.referencesen6. Dytyatkovs`ka, E. M. (2011). The state of lipids` peroxidation at patients suffering from pollinosis. Rhinology, 3, 11–16. [in Ukraine].
dc.relation.referencesen7. Richter, C. (1987). Biophysical consequence of lipid peroxidation in membranes. Chem Phys Lipids, 44 (2–4), 175–89. https://doi.org/10.1016/0009-3084(87)90049-1
dc.relation.referencesen8. Boldyrev, A. A., Yuneva, M. O., Sorokina, E. V., Kramarenko, G. G., Fedorova, T. N., Konovalova, G. G., and Lankin, V. Z. (2001). Antioxidant Systems in Tissues of Senescence Accelerated Mice. Biochemistry, 66(10), 1157–1163. [in Russian].
dc.relation.referencesen9. Lushchak, V. I., Bagnyukova, T. V., Luzhna L. I. (2006). Indices of oxidative stress.2. Lipid peroxides. The Ukrainian Biochemical Journal, 78(5), 113–119. [in Ukraine].
dc.relation.referencesen10. Tarchevsky I. A. (1992). The degradation processes in plants. Russian Journal of Plant Physiology, 39(6), 1215–1223. [in Russian].
dc.relation.referencesen11. Kubyshkin, A. V., Avidzba, A. M., Borisyuk, V. S., Stoyanov, V. S. (2017). Polyphenols of red grapes in wine and concentrates for use in rehabilitation technologies. Agricultural Biology, 52(3), 622–630. [in Russian].
dc.relation.referencesen12. Safaei, N., Babaei, H., Azarfarin, R., Jodati, A. R., Yaghoubi, A., Sheikhalizadeh, M. A.. (2017). Comparative Effect of Grape Seed Extract (Vitis vinifera) and Ascorbic Acid in Oxidative Stress Induced by On-Pump Coronary Artery Bypass Surgery. Annals of Cardiac Anaesthesia, 20(1), 45–51. https://doi.org/10.4103/0971-9784.197834
dc.relation.referencesen13. Brazinha, C, Cadima, M, Crespo, J. G. (2014) Optimization of extraction of bioactive compounds from different types of grape pomace produced at wineries and distilleries. Journal of Food Science. 79(6), E1142-1149. https://doi.org/10.1111/1750-3841.12476.
dc.relation.referencesen14. Kustova, I. A., Makarova, N. V., Gudkova, A. M. (2017). Obtaining extract from grape secondary raw materials, Khimija rastitel'nogo syr'ja [Chemistry of plant raw material] 3, 175–184. [in Russian]. https://doi.org/10.14258/jcprm.2017031659
dc.relation.referencesen15. Batkova, I. A., Makarova, N. V., Yashina, I. A., Novikova, M. N., Smirnova, N. V. (2014). Preparation of Extracts from Husks and Grape Seeds with High Antioxidant Activity. Food Industry, 2, 68–70. [in Russian].
dc.relation.referencesen16. Marynin A., Zaxarevych, V., Rogovyj, I., Farysyeyev, A., Sukmanov, V. (2016). Patent Ukraine UA 107175U. Kyiv: SOE Ukrainian Intellectual Property Institute. [in Ukraine].
dc.relation.referencesen17. Morgan, G. A., Leech, N. L., Gloeckner, G. W., Barrett, K. C. (2012). IBM SPSS for Introductory Statistics. In: Use and Interpretation. Fourth Edition. Routledge Taylor & Francis Group, New York. 256.
dc.relation.referencesen18. Molyneux, P. (2004). The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Journal of Science and Technology, 26(2), 211–219.
dc.relation.urihttps://doi.org/10.1016/j.wasman.2017.11.011
dc.relation.urihttp://dx.doi.org/10.5539/jfr.v3n2p91
dc.relation.urihttps://doi.org/10.1016/0009-3084(87)90049-1
dc.relation.urihttps://doi.org/10.4103/0971-9784.197834
dc.relation.urihttps://doi.org/10.1111/1750-3841.12476
dc.relation.urihttps://doi.org/10.14258/jcprm.2017031659
dc.rights.holder© Національний університет “Львівська політехніка”, 2020
dc.subjectекстракти виноградного шроту
dc.subjectрадикал-поглинальна активність
dc.subjectантиоксидантні властивості
dc.subjectextracts of grape marc
dc.subjectradical absorption activity
dc.subjectantioxidant properties
dc.titleResearch of antioxidant properties of grape marc extracts as perspective pharmaceutical and cosmetic products
dc.title.alternativeДослідження антиоксидантних властивостей екстрактів з виноградного жмиху як перспективних фармацевтичних та косметичних засобів
dc.typeArticle

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Chemistry, Technology and Application of Substances. – 2020. – Vol. 3, No. 2