Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone

dc.citation.epage43
dc.citation.issue1
dc.citation.spage33
dc.contributor.affiliationНаціональний університет “Львівська політехніка”
dc.contributor.affiliationLviv Polytechnic National University
dc.contributor.authorСмірнова, О. Я.
dc.contributor.authorЯтчишин, Й. Й.
dc.contributor.authorКолобич, С. В.
dc.contributor.authorПолюжин, І. П.
dc.contributor.authorSmirnova, O. Ya.
dc.contributor.authorYatchyshyn, Yo. Yo.
dc.contributor.authorKolobych, S. V.
dc.contributor.authorPoliuzhyn, I. P.
dc.coverage.placenameЛьвів
dc.coverage.placenameLviv
dc.date.accessioned2024-01-22T08:14:55Z
dc.date.available2024-01-22T08:14:55Z
dc.date.created2021-03-16
dc.date.issued2021-03-16
dc.description.abstractДосліджено хроматографічні характеристики восьми ароматичних похідних 3-хлоро-1,4- нафтохінону в умовах нормальнофазової тонкошарової хроматографії для бінарної мобільної фази на основі бензолу і таких полярних розчинників, як хлороформ, ацетон, ацетонітрил, метанол і пропан-2-ол. Нахил лінійних залежностей утримування досліджених сполук від концентрації полярного компонента в мобільній фазі задовільно корелює із площею, яку займає адсорбована молекула аналіту на нерухомій фазі. Відтинок у рівнянні Сочевінського залежить від полярного компонента мобільної фази.
dc.description.abstractThe chromatographic characteristics were investigated for eight aromatic derivatives of 3- chloro-1,4-naphthoquinone under conditions of normal-phase thin-layer chromatography for benzene-based binary mobile phase and such polar solvents as chloroform, acetone, acetonitrile, methanol and propan-2-ol. The slope of linear retention dependencies for the investigated compounds on the concentration of the polar component in the mobile phase satisfactorily correlates with the area occupied by the adsorbed analyte molecule in the stationary phase. The intercept in the Soczewinski equation depends on the polar component of the mobile phase.
dc.format.extent33-43
dc.format.pages11
dc.identifier.citationNormal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone / O. Ya. Smirnova, Yo. Yo. Yatchyshyn, S. V. Kolobych, I. P. Poliuzhyn // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2021. — Vol 4. — No 1. — P. 33–43.
dc.identifier.citationenNormal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone / O. Ya. Smirnova, Yo. Yo. Yatchyshyn, S. V. Kolobych, I. P. Poliuzhyn // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2021. — Vol 4. — No 1. — P. 33–43.
dc.identifier.doidoi.org/ 10.23939/ctas2021.01.033
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/60870
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofChemistry, Technology and Application of Substances, 1 (4), 2021
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dc.relation.references5. Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Ruchirawat, S., & Prachayasittikul, V. (2014). Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives. European Journal of Medicinal Chemistry, 84, 247–263. doi:10.1016/j.ejmech.2014.07.024
dc.relation.references6. Ibis, C., Shntaif, H., Bahar, H., & Ayla, S. (2015). An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents. Journal of the Serbian Chemical Society, 80(6), 731–738. doi:10.2298/jsc141124021i
dc.relation.references7. Shakh, Y. U., Romanenko, I., Slesarchuk, M., Syngaevsky, V., Kovalchuk, O., Bolibrukh, K., Karkhut, A., … O., Polovkovych, S. & Novikov, V. (2017). Synthesis and Antimicrobial Activity of 1,4-Naphthoquinones Derivatives with [1,2,4]-Triazole-3-thione Substitution. Indian Journal of Pharmaceutical Sciences, 79(4), 650–654. doi:10.4172/pharmaceutical-sciences.1000275
dc.relation.references8. Tandon, V. K., Singh, R. V., & Yadav, D. B. (2004). Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorganic & Medicinal Chemistry Letters, 14(11), 2901–2904. doi:10.1016/j.bmcl.2004.03.047
dc.relation.references9. Phillips, R. M., Jaffar, M., Maitland, D. J., Loadman, P. M., …, Patterson, A.V. & Stratford, I. J. (2004). Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Biochemical Pharmacology, 68(11), 2107–2116. doi:10.1016/j.bcp.2004.08.007
dc.relation.references10. Mathew, N., Karunan, T., Srinivasan, L., & Muthuswamy, K. (2010). Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents. Drug Development Research, 71, 188–196. doi:10.1002/ddr.20357
dc.relation.references11. Kurban, S., Deniz, N. G., Sayil, C., Ozyurek, M., Guclu, K., Stasevych, M., Zvarych, V., KomarovskaPorokhnyavets, O. & Novikov, V. (2019). Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1,4-Naphtho- and Benzoquinone Derivatives Containing N-, S-, O-Substituted. Heteroatom Chemistry, 2019, 1–12. doi:10.1155/2019/1658417
dc.relation.references12. Yildirim, H. (2017). Synthesis and Structural Analysis of Some New Sulfanyl Amino 1,4-Naphthoquinone Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 5(1), 149–158. doi: 10.18596/jotcsa.335894
dc.relation.references13. Kotakemori, M., & Okada, K. (1966). Thinlayer Chromatography of Some Substituted Naphthoquinones. Agricultural and Biological Chemistry, 30(9), 935–936. doi: 10.1271/bbb1961.30.935
dc.relation.references14. Smirnova O. Ya., Polyuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Normalnofazova tonkosharova khromatografiya dlya cyklichnyh pokhidnyh 3-hloro-1,4-naftohinonu. Visnyk Nacionalnogo universytetu “Lvivska politehnika”. Himiya, texnologiya rechovyn ta yih zastosuvannya, 886, 14–22.
dc.relation.references15. Smirnova O. Ya., Poliuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Zalezhnosti mizh strukturoiu aminokyslotnykh pokhidnykh 3-khlor-1,4-naftokhinonu ta yikh utrymuvanniam v umovakh priamofazovoi tonkosharovoi khromatohrafii. Pytannia khimii ta khimichnoi tekhnolohii, 4 (119), S. 59–68. Retrieved from: http://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf
dc.relation.references16. Poliuzhyn Ihor, Smirnova Oksana, Yatchyshyn Yosyp (2018). Thin Layer Chromatography for Some Derivatives of 1,4-Naphthoquinone. – 8-th International Joint Youth Science Forum “Litteris et Artibus” (November, 22-24, 2018) / Proceedings. Lviv: “Lviv Polytechnic Press” (1 CD-ROM). P. 162–167.
dc.relation.references17. Snyder L. R. (1968). Principles of adsorption chromatography. New York: Dekker
dc.relation.references18. Snyder L. R., Kirkland J. J., Dolan J. W. (2010). Introduction to Modern Liquid Chromatography. John Wiley & Sons, Inc.
dc.relation.references19. Shandrenko, S. H., Holovin, A. S., Dmytrenko, M. P., Yurchenko, A. I., Babycheva, O. F. (2002). Kompiuterna reiestratsiia ta analiz rezultativ tonkosharovoi khromatohrafii. Zhurnal Khromatohrafichnoho tovarystva, 2(4), 22–30. doi: 10.15407/zht.2002.2.4.22
dc.relation.references20. Snyder, L. R. (1974). Classification of the solvent properties of common liquids. Journal of Chromatography A, 92(2), 223–230. doi: 10.1016/s0021-9673(00)85732-5
dc.relation.references21. Snyder, L. R., Carr, P. W., & Rutan, S. C. (1993). Solvatochromically based solvent-selectivity triangle. Journal of Chromatography A, 656 (1–2), 537–547. doi:10.1016/0021-9673(93)80818-s
dc.relation.referencesen1. Bechtold T. (2010). Handbook of natural colorants. Chichester: Wiley.
dc.relation.referencesen2. Ibis Cemil, Tuyun Amac Fatih, Bahar Hakan, Ayla Sibel Sahinler, Stasevych Maryna V., Musyanovych Rostyslav … Novikov Volodymyr (2013). Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents. Medicinal Chemistry Research, 22(6), 2879–2888. doi:10.1007/s00044-012-0300-y
dc.relation.referencesen3. Deniz, Nahide Gülşah; Ibis, Cemil; Gokmen, Zeliha; Stasevych, Maryna; Novikov, Volodymyr; … Ozyurek, Mustafa; Guclu, Kubilay; Karakas, Didem; Ulukaya, Engin (2015). Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones. Chemical and Pharmaceutical Bulletin, 63(12), 1029-1039. doi:10.1248/cpb.P.15-00607
dc.relation.referencesen4. Sieveking, Ivan; Thomas, Pablo; Estévez, Juan C.; Quiñones, Natalia; Cuéllar, Mauricio A.; Villena, Juan; Espinosa-Bustos, Christian; Fierro, Angélica; Tapia,Ricardo A.; Maya, Juan D.; López-Muñoz, Rodrigo; Cassels, Bruce K.; Estévez, Ramon J.; Salas, Cristian O. (2014). 2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities. Bioorganic & Medicinal Chemistry, 22(17), 4609–4620. doi:10.1016/j.bmc.2014.07.030
dc.relation.referencesen5. Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Ruchirawat, S., & Prachayasittikul, V. (2014). Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives. European Journal of Medicinal Chemistry, 84, 247–263. doi:10.1016/j.ejmech.2014.07.024
dc.relation.referencesen6. Ibis, C., Shntaif, H., Bahar, H., & Ayla, S. (2015). An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents. Journal of the Serbian Chemical Society, 80(6), 731–738. doi:10.2298/jsc141124021i
dc.relation.referencesen7. Shakh, Y. U., Romanenko, I., Slesarchuk, M., Syngaevsky, V., Kovalchuk, O., Bolibrukh, K., Karkhut, A., … O., Polovkovych, S. & Novikov, V. (2017). Synthesis and Antimicrobial Activity of 1,4-Naphthoquinones Derivatives with [1,2,4]-Triazole-3-thione Substitution. Indian Journal of Pharmaceutical Sciences, 79(4), 650–654. doi:10.4172/pharmaceutical-sciences.1000275
dc.relation.referencesen8. Tandon, V. K., Singh, R. V., & Yadav, D. B. (2004). Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorganic & Medicinal Chemistry Letters, 14(11), 2901–2904. doi:10.1016/j.bmcl.2004.03.047
dc.relation.referencesen9. Phillips, R. M., Jaffar, M., Maitland, D. J., Loadman, P. M., …, Patterson, A.V. & Stratford, I. J. (2004). Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Biochemical Pharmacology, 68(11), 2107–2116. doi:10.1016/j.bcp.2004.08.007
dc.relation.referencesen10. Mathew, N., Karunan, T., Srinivasan, L., & Muthuswamy, K. (2010). Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents. Drug Development Research, 71, 188–196. doi:10.1002/ddr.20357
dc.relation.referencesen11. Kurban, S., Deniz, N. G., Sayil, C., Ozyurek, M., Guclu, K., Stasevych, M., Zvarych, V., KomarovskaPorokhnyavets, O. & Novikov, V. (2019). Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1,4-Naphtho- and Benzoquinone Derivatives Containing N-, S-, O-Substituted. Heteroatom Chemistry, 2019, 1–12. doi:10.1155/2019/1658417
dc.relation.referencesen12. Yildirim, H. (2017). Synthesis and Structural Analysis of Some New Sulfanyl Amino 1,4-Naphthoquinone Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 5(1), 149–158. doi: 10.18596/jotcsa.335894
dc.relation.referencesen13. Kotakemori, M., & Okada, K. (1966). Thinlayer Chromatography of Some Substituted Naphthoquinones. Agricultural and Biological Chemistry, 30(9), 935–936. doi: 10.1271/bbb1961.30.935
dc.relation.referencesen14. Smirnova O. Ya., Polyuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Normalnofazova tonkosharova khromatografiya dlya cyklichnyh pokhidnyh 3-hloro-1,4-naftohinonu. Visnyk Nacionalnogo universytetu "Lvivska politehnika". Himiya, texnologiya rechovyn ta yih zastosuvannya, 886, 14–22.
dc.relation.referencesen15. Smirnova O. Ya., Poliuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Zalezhnosti mizh strukturoiu aminokyslotnykh pokhidnykh 3-khlor-1,4-naftokhinonu ta yikh utrymuvanniam v umovakh priamofazovoi tonkosharovoi khromatohrafii. Pytannia khimii ta khimichnoi tekhnolohii, 4 (119), S. 59–68. Retrieved from: http://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf
dc.relation.referencesen16. Poliuzhyn Ihor, Smirnova Oksana, Yatchyshyn Yosyp (2018). Thin Layer Chromatography for Some Derivatives of 1,4-Naphthoquinone, 8-th International Joint Youth Science Forum "Litteris et Artibus" (November, 22-24, 2018), Proceedings. Lviv: "Lviv Polytechnic Press" (1 CD-ROM). P. 162–167.
dc.relation.referencesen17. Snyder L. R. (1968). Principles of adsorption chromatography. New York: Dekker
dc.relation.referencesen18. Snyder L. R., Kirkland J. J., Dolan J. W. (2010). Introduction to Modern Liquid Chromatography. John Wiley & Sons, Inc.
dc.relation.referencesen19. Shandrenko, S. H., Holovin, A. S., Dmytrenko, M. P., Yurchenko, A. I., Babycheva, O. F. (2002). Kompiuterna reiestratsiia ta analiz rezultativ tonkosharovoi khromatohrafii. Zhurnal Khromatohrafichnoho tovarystva, 2(4), 22–30. doi: 10.15407/zht.2002.2.4.22
dc.relation.referencesen20. Snyder, L. R. (1974). Classification of the solvent properties of common liquids. Journal of Chromatography A, 92(2), 223–230. doi: 10.1016/s0021-9673(00)85732-5
dc.relation.referencesen21. Snyder, L. R., Carr, P. W., & Rutan, S. C. (1993). Solvatochromically based solvent-selectivity triangle. Journal of Chromatography A, 656 (1–2), 537–547. doi:10.1016/0021-9673(93)80818-s
dc.relation.urihttp://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf
dc.rights.holder© Національний університет “Львівська політехніка”, 2021
dc.subjectтонкошарова хроматографія
dc.subjectнафтохінон-1
dc.subject4
dc.subjectароматичні похідні
dc.subjectсклад елюента
dc.subjectрівняння Сочевінського
dc.subjectthin-layer chromatography
dc.subjectnaphthoquinone-1
dc.subject4
dc.subjectaromatic derivatives
dc.subjectcomposition of the eluent
dc.subjectSoczewinski equation
dc.titleNormal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone
dc.title.alternativeНормальнофазова тонкошарова хроматографія для ароматичних похідних 3-хлоро-1,4-нафтохінону
dc.typeArticle

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