Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone
dc.citation.epage | 43 | |
dc.citation.issue | 1 | |
dc.citation.spage | 33 | |
dc.contributor.affiliation | Національний університет “Львівська політехніка” | |
dc.contributor.affiliation | Lviv Polytechnic National University | |
dc.contributor.author | Смірнова, О. Я. | |
dc.contributor.author | Ятчишин, Й. Й. | |
dc.contributor.author | Колобич, С. В. | |
dc.contributor.author | Полюжин, І. П. | |
dc.contributor.author | Smirnova, O. Ya. | |
dc.contributor.author | Yatchyshyn, Yo. Yo. | |
dc.contributor.author | Kolobych, S. V. | |
dc.contributor.author | Poliuzhyn, I. P. | |
dc.coverage.placename | Львів | |
dc.coverage.placename | Lviv | |
dc.date.accessioned | 2024-01-22T08:14:55Z | |
dc.date.available | 2024-01-22T08:14:55Z | |
dc.date.created | 2021-03-16 | |
dc.date.issued | 2021-03-16 | |
dc.description.abstract | Досліджено хроматографічні характеристики восьми ароматичних похідних 3-хлоро-1,4- нафтохінону в умовах нормальнофазової тонкошарової хроматографії для бінарної мобільної фази на основі бензолу і таких полярних розчинників, як хлороформ, ацетон, ацетонітрил, метанол і пропан-2-ол. Нахил лінійних залежностей утримування досліджених сполук від концентрації полярного компонента в мобільній фазі задовільно корелює із площею, яку займає адсорбована молекула аналіту на нерухомій фазі. Відтинок у рівнянні Сочевінського залежить від полярного компонента мобільної фази. | |
dc.description.abstract | The chromatographic characteristics were investigated for eight aromatic derivatives of 3- chloro-1,4-naphthoquinone under conditions of normal-phase thin-layer chromatography for benzene-based binary mobile phase and such polar solvents as chloroform, acetone, acetonitrile, methanol and propan-2-ol. The slope of linear retention dependencies for the investigated compounds on the concentration of the polar component in the mobile phase satisfactorily correlates with the area occupied by the adsorbed analyte molecule in the stationary phase. The intercept in the Soczewinski equation depends on the polar component of the mobile phase. | |
dc.format.extent | 33-43 | |
dc.format.pages | 11 | |
dc.identifier.citation | Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone / O. Ya. Smirnova, Yo. Yo. Yatchyshyn, S. V. Kolobych, I. P. Poliuzhyn // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2021. — Vol 4. — No 1. — P. 33–43. | |
dc.identifier.citationen | Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone / O. Ya. Smirnova, Yo. Yo. Yatchyshyn, S. V. Kolobych, I. P. Poliuzhyn // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2021. — Vol 4. — No 1. — P. 33–43. | |
dc.identifier.doi | doi.org/ 10.23939/ctas2021.01.033 | |
dc.identifier.uri | https://ena.lpnu.ua/handle/ntb/60870 | |
dc.language.iso | en | |
dc.publisher | Видавництво Львівської політехніки | |
dc.publisher | Lviv Politechnic Publishing House | |
dc.relation.ispartof | Chemistry, Technology and Application of Substances, 1 (4), 2021 | |
dc.relation.references | 1. Bechtold T. (2010). Handbook of natural colorants. Chichester: Wiley. | |
dc.relation.references | 2. Ibis Cemil, Tuyun Amac Fatih, Bahar Hakan, Ayla Sibel Sahinler, Stasevych Maryna V., Musyanovych Rostyslav … Novikov Volodymyr (2013). Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents. Medicinal Chemistry Research, 22(6), 2879–2888. doi:10.1007/s00044-012-0300-y | |
dc.relation.references | 3. Deniz, Nahide Gülşah; Ibis, Cemil; Gokmen, Zeliha; Stasevych, Maryna; Novikov, Volodymyr; … Ozyurek, Mustafa; Guclu, Kubilay; Karakas, Didem; Ulukaya, Engin (2015). Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones. Chemical and Pharmaceutical Bulletin, 63(12), 1029-1039. doi:10.1248/cpb.c15-00607 | |
dc.relation.references | 4. Sieveking, Ivan; Thomas, Pablo; Estévez, Juan C.; Quiñones, Natalia; Cuéllar, Mauricio A.; Villena, Juan; Espinosa-Bustos, Christian; Fierro, Angélica; Tapia,Ricardo A.; Maya, Juan D.; López-Muñoz, Rodrigo; Cassels, Bruce K.; Estévez, Ramon J.; Salas, Cristian O. (2014). 2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities. Bioorganic & Medicinal Chemistry, 22(17), 4609–4620. doi:10.1016/j.bmc.2014.07.030 | |
dc.relation.references | 5. Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Ruchirawat, S., & Prachayasittikul, V. (2014). Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives. European Journal of Medicinal Chemistry, 84, 247–263. doi:10.1016/j.ejmech.2014.07.024 | |
dc.relation.references | 6. Ibis, C., Shntaif, H., Bahar, H., & Ayla, S. (2015). An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents. Journal of the Serbian Chemical Society, 80(6), 731–738. doi:10.2298/jsc141124021i | |
dc.relation.references | 7. Shakh, Y. U., Romanenko, I., Slesarchuk, M., Syngaevsky, V., Kovalchuk, O., Bolibrukh, K., Karkhut, A., … O., Polovkovych, S. & Novikov, V. (2017). Synthesis and Antimicrobial Activity of 1,4-Naphthoquinones Derivatives with [1,2,4]-Triazole-3-thione Substitution. Indian Journal of Pharmaceutical Sciences, 79(4), 650–654. doi:10.4172/pharmaceutical-sciences.1000275 | |
dc.relation.references | 8. Tandon, V. K., Singh, R. V., & Yadav, D. B. (2004). Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorganic & Medicinal Chemistry Letters, 14(11), 2901–2904. doi:10.1016/j.bmcl.2004.03.047 | |
dc.relation.references | 9. Phillips, R. M., Jaffar, M., Maitland, D. J., Loadman, P. M., …, Patterson, A.V. & Stratford, I. J. (2004). Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Biochemical Pharmacology, 68(11), 2107–2116. doi:10.1016/j.bcp.2004.08.007 | |
dc.relation.references | 10. Mathew, N., Karunan, T., Srinivasan, L., & Muthuswamy, K. (2010). Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents. Drug Development Research, 71, 188–196. doi:10.1002/ddr.20357 | |
dc.relation.references | 11. Kurban, S., Deniz, N. G., Sayil, C., Ozyurek, M., Guclu, K., Stasevych, M., Zvarych, V., KomarovskaPorokhnyavets, O. & Novikov, V. (2019). Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1,4-Naphtho- and Benzoquinone Derivatives Containing N-, S-, O-Substituted. Heteroatom Chemistry, 2019, 1–12. doi:10.1155/2019/1658417 | |
dc.relation.references | 12. Yildirim, H. (2017). Synthesis and Structural Analysis of Some New Sulfanyl Amino 1,4-Naphthoquinone Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 5(1), 149–158. doi: 10.18596/jotcsa.335894 | |
dc.relation.references | 13. Kotakemori, M., & Okada, K. (1966). Thinlayer Chromatography of Some Substituted Naphthoquinones. Agricultural and Biological Chemistry, 30(9), 935–936. doi: 10.1271/bbb1961.30.935 | |
dc.relation.references | 14. Smirnova O. Ya., Polyuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Normalnofazova tonkosharova khromatografiya dlya cyklichnyh pokhidnyh 3-hloro-1,4-naftohinonu. Visnyk Nacionalnogo universytetu “Lvivska politehnika”. Himiya, texnologiya rechovyn ta yih zastosuvannya, 886, 14–22. | |
dc.relation.references | 15. Smirnova O. Ya., Poliuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Zalezhnosti mizh strukturoiu aminokyslotnykh pokhidnykh 3-khlor-1,4-naftokhinonu ta yikh utrymuvanniam v umovakh priamofazovoi tonkosharovoi khromatohrafii. Pytannia khimii ta khimichnoi tekhnolohii, 4 (119), S. 59–68. Retrieved from: http://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf | |
dc.relation.references | 16. Poliuzhyn Ihor, Smirnova Oksana, Yatchyshyn Yosyp (2018). Thin Layer Chromatography for Some Derivatives of 1,4-Naphthoquinone. – 8-th International Joint Youth Science Forum “Litteris et Artibus” (November, 22-24, 2018) / Proceedings. Lviv: “Lviv Polytechnic Press” (1 CD-ROM). P. 162–167. | |
dc.relation.references | 17. Snyder L. R. (1968). Principles of adsorption chromatography. New York: Dekker | |
dc.relation.references | 18. Snyder L. R., Kirkland J. J., Dolan J. W. (2010). Introduction to Modern Liquid Chromatography. John Wiley & Sons, Inc. | |
dc.relation.references | 19. Shandrenko, S. H., Holovin, A. S., Dmytrenko, M. P., Yurchenko, A. I., Babycheva, O. F. (2002). Kompiuterna reiestratsiia ta analiz rezultativ tonkosharovoi khromatohrafii. Zhurnal Khromatohrafichnoho tovarystva, 2(4), 22–30. doi: 10.15407/zht.2002.2.4.22 | |
dc.relation.references | 20. Snyder, L. R. (1974). Classification of the solvent properties of common liquids. Journal of Chromatography A, 92(2), 223–230. doi: 10.1016/s0021-9673(00)85732-5 | |
dc.relation.references | 21. Snyder, L. R., Carr, P. W., & Rutan, S. C. (1993). Solvatochromically based solvent-selectivity triangle. Journal of Chromatography A, 656 (1–2), 537–547. doi:10.1016/0021-9673(93)80818-s | |
dc.relation.referencesen | 1. Bechtold T. (2010). Handbook of natural colorants. Chichester: Wiley. | |
dc.relation.referencesen | 2. Ibis Cemil, Tuyun Amac Fatih, Bahar Hakan, Ayla Sibel Sahinler, Stasevych Maryna V., Musyanovych Rostyslav … Novikov Volodymyr (2013). Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents. Medicinal Chemistry Research, 22(6), 2879–2888. doi:10.1007/s00044-012-0300-y | |
dc.relation.referencesen | 3. Deniz, Nahide Gülşah; Ibis, Cemil; Gokmen, Zeliha; Stasevych, Maryna; Novikov, Volodymyr; … Ozyurek, Mustafa; Guclu, Kubilay; Karakas, Didem; Ulukaya, Engin (2015). Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones. Chemical and Pharmaceutical Bulletin, 63(12), 1029-1039. doi:10.1248/cpb.P.15-00607 | |
dc.relation.referencesen | 4. Sieveking, Ivan; Thomas, Pablo; Estévez, Juan C.; Quiñones, Natalia; Cuéllar, Mauricio A.; Villena, Juan; Espinosa-Bustos, Christian; Fierro, Angélica; Tapia,Ricardo A.; Maya, Juan D.; López-Muñoz, Rodrigo; Cassels, Bruce K.; Estévez, Ramon J.; Salas, Cristian O. (2014). 2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities. Bioorganic & Medicinal Chemistry, 22(17), 4609–4620. doi:10.1016/j.bmc.2014.07.030 | |
dc.relation.referencesen | 5. Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Ruchirawat, S., & Prachayasittikul, V. (2014). Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives. European Journal of Medicinal Chemistry, 84, 247–263. doi:10.1016/j.ejmech.2014.07.024 | |
dc.relation.referencesen | 6. Ibis, C., Shntaif, H., Bahar, H., & Ayla, S. (2015). An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents. Journal of the Serbian Chemical Society, 80(6), 731–738. doi:10.2298/jsc141124021i | |
dc.relation.referencesen | 7. Shakh, Y. U., Romanenko, I., Slesarchuk, M., Syngaevsky, V., Kovalchuk, O., Bolibrukh, K., Karkhut, A., … O., Polovkovych, S. & Novikov, V. (2017). Synthesis and Antimicrobial Activity of 1,4-Naphthoquinones Derivatives with [1,2,4]-Triazole-3-thione Substitution. Indian Journal of Pharmaceutical Sciences, 79(4), 650–654. doi:10.4172/pharmaceutical-sciences.1000275 | |
dc.relation.referencesen | 8. Tandon, V. K., Singh, R. V., & Yadav, D. B. (2004). Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorganic & Medicinal Chemistry Letters, 14(11), 2901–2904. doi:10.1016/j.bmcl.2004.03.047 | |
dc.relation.referencesen | 9. Phillips, R. M., Jaffar, M., Maitland, D. J., Loadman, P. M., …, Patterson, A.V. & Stratford, I. J. (2004). Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Biochemical Pharmacology, 68(11), 2107–2116. doi:10.1016/j.bcp.2004.08.007 | |
dc.relation.referencesen | 10. Mathew, N., Karunan, T., Srinivasan, L., & Muthuswamy, K. (2010). Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents. Drug Development Research, 71, 188–196. doi:10.1002/ddr.20357 | |
dc.relation.referencesen | 11. Kurban, S., Deniz, N. G., Sayil, C., Ozyurek, M., Guclu, K., Stasevych, M., Zvarych, V., KomarovskaPorokhnyavets, O. & Novikov, V. (2019). Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1,4-Naphtho- and Benzoquinone Derivatives Containing N-, S-, O-Substituted. Heteroatom Chemistry, 2019, 1–12. doi:10.1155/2019/1658417 | |
dc.relation.referencesen | 12. Yildirim, H. (2017). Synthesis and Structural Analysis of Some New Sulfanyl Amino 1,4-Naphthoquinone Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 5(1), 149–158. doi: 10.18596/jotcsa.335894 | |
dc.relation.referencesen | 13. Kotakemori, M., & Okada, K. (1966). Thinlayer Chromatography of Some Substituted Naphthoquinones. Agricultural and Biological Chemistry, 30(9), 935–936. doi: 10.1271/bbb1961.30.935 | |
dc.relation.referencesen | 14. Smirnova O. Ya., Polyuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Normalnofazova tonkosharova khromatografiya dlya cyklichnyh pokhidnyh 3-hloro-1,4-naftohinonu. Visnyk Nacionalnogo universytetu "Lvivska politehnika". Himiya, texnologiya rechovyn ta yih zastosuvannya, 886, 14–22. | |
dc.relation.referencesen | 15. Smirnova O. Ya., Poliuzhyn I. P., Yatchyshyn Yo. Yo. (2018). Zalezhnosti mizh strukturoiu aminokyslotnykh pokhidnykh 3-khlor-1,4-naftokhinonu ta yikh utrymuvanniam v umovakh priamofazovoi tonkosharovoi khromatohrafii. Pytannia khimii ta khimichnoi tekhnolohii, 4 (119), S. 59–68. Retrieved from: http://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf | |
dc.relation.referencesen | 16. Poliuzhyn Ihor, Smirnova Oksana, Yatchyshyn Yosyp (2018). Thin Layer Chromatography for Some Derivatives of 1,4-Naphthoquinone, 8-th International Joint Youth Science Forum "Litteris et Artibus" (November, 22-24, 2018), Proceedings. Lviv: "Lviv Polytechnic Press" (1 CD-ROM). P. 162–167. | |
dc.relation.referencesen | 17. Snyder L. R. (1968). Principles of adsorption chromatography. New York: Dekker | |
dc.relation.referencesen | 18. Snyder L. R., Kirkland J. J., Dolan J. W. (2010). Introduction to Modern Liquid Chromatography. John Wiley & Sons, Inc. | |
dc.relation.referencesen | 19. Shandrenko, S. H., Holovin, A. S., Dmytrenko, M. P., Yurchenko, A. I., Babycheva, O. F. (2002). Kompiuterna reiestratsiia ta analiz rezultativ tonkosharovoi khromatohrafii. Zhurnal Khromatohrafichnoho tovarystva, 2(4), 22–30. doi: 10.15407/zht.2002.2.4.22 | |
dc.relation.referencesen | 20. Snyder, L. R. (1974). Classification of the solvent properties of common liquids. Journal of Chromatography A, 92(2), 223–230. doi: 10.1016/s0021-9673(00)85732-5 | |
dc.relation.referencesen | 21. Snyder, L. R., Carr, P. W., & Rutan, S. C. (1993). Solvatochromically based solvent-selectivity triangle. Journal of Chromatography A, 656 (1–2), 537–547. doi:10.1016/0021-9673(93)80818-s | |
dc.relation.uri | http://udhtu.edu.ua/public/userfiles/file/VHHT/2018/4/Smirnova.pdf | |
dc.rights.holder | © Національний університет “Львівська політехніка”, 2021 | |
dc.subject | тонкошарова хроматографія | |
dc.subject | нафтохінон-1 | |
dc.subject | 4 | |
dc.subject | ароматичні похідні | |
dc.subject | склад елюента | |
dc.subject | рівняння Сочевінського | |
dc.subject | thin-layer chromatography | |
dc.subject | naphthoquinone-1 | |
dc.subject | 4 | |
dc.subject | aromatic derivatives | |
dc.subject | composition of the eluent | |
dc.subject | Soczewinski equation | |
dc.title | Normal phase thin layer chromatography for aromatic derivatives of 3-chloro-1,4-naphtochinone | |
dc.title.alternative | Нормальнофазова тонкошарова хроматографія для ароматичних похідних 3-хлоро-1,4-нафтохінону | |
dc.type | Article |
Files
License bundle
1 - 1 of 1