Hydrogels in Biomedicine: Granular Controlled Release Systems Based on 2-Hydroxyethyl Methacrylate Copolymers. A Review

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dc.citation.epage156
dc.citation.issue2
dc.citation.journalTitleХімія та хімічна технологія
dc.citation.spage143
dc.citation.volume18
dc.contributor.affiliationLviv Polytechnic National University
dc.contributor.authorSemenyuk, Nataliya
dc.contributor.authorDudok, Galyna
dc.contributor.authorSkorokhoda, Volodymyr
dc.coverage.placenameЛьвів
dc.coverage.placenameLviv
dc.date.accessioned2025-09-24T06:47:53Z
dc.date.created2024-02-27
dc.date.issued2024-02-27
dc.description.abstractПроаналізовано й узагальнено останні досягнення в галузі створення полімерних систем для пристроїв контрольованого вивільнення речовин у середовище дії на основі гідрогелевих матеріалів. Представлено можливі напрями доставки ліків, зокрема за допомогою гранульних гідрогелів, які працюють за принципом сорбція лікарського засобу вивільнення його в організмі. Проаналізовано дослідження закономірностей синтезу, структури, властивостей і перспектив застосування гранульних гідрогелів на основі 2-гідроксіетилметакрилату та його кополімерів, зокрема з полівінілпіролідоном, як систем контрольованого вивільнення речовин, зокрема ліків.
dc.description.abstractThe article analyzes and summarizes the latest achievements in the field of polymer systems for controlled release devices based on hydrogel materials. Possible directions of drug delivery are presented, including the use of granular hydrogels, which work on the principle of drug sorption − release in the body. The research on the synthesis regularities, structure, properties, and prospects for the use of granular hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and its copolymers, in particular with polyvinylpyrrolidone (PVP), as systems for the controlled release of substances, in particular, drugs, is analyzed.
dc.format.extent143-156
dc.format.pages14
dc.identifier.citationSemenyuk N. Hydrogels in Biomedicine: Granular Controlled Release Systems Based on 2-Hydroxyethyl Methacrylate Copolymers. A Review / Nataliya Semenyuk, Galyna Dudok, Volodymyr Skorokhoda // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2024. — Vol 18. — No 2. — P. 143–156.
dc.identifier.citationenSemenyuk N. Hydrogels in Biomedicine: Granular Controlled Release Systems Based on 2-Hydroxyethyl Methacrylate Copolymers. A Review / Nataliya Semenyuk, Galyna Dudok, Volodymyr Skorokhoda // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2024. — Vol 18. — No 2. — P. 143–156.
dc.identifier.doidoi.org/10.23939/chcht18.02.143
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/111794
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofХімія та хімічна технологія, 2 (18), 2024
dc.relation.ispartofChemistry & Chemical Technology, 2 (18), 2024
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dc.relation.urihttps://doi.org/10.23939/chcht06.03.301
dc.relation.urihttp://dx.doi.org/10.32434/0321-4095-2022-142-3-67-73
dc.relation.urihttps://doi.org/10.23939/chcht03.02.117
dc.relation.urihttp://nbuv.gov.ua/UJRN/VNULPX_2015_812_71
dc.rights.holder© Національний університет “Львівська політехніка”, 2024
dc.rights.holder© Semenyuk N., Dudok G., Skorokhoda V., 2024
dc.subjectпролонгатори ліків
dc.subjectгідрогелі
dc.subjectгранульні кополімери
dc.subject2-гідроксіетилметакрилат
dc.subjectсуспензійна полімеризація
dc.subjectполівінілпіролідон
dc.subjectdrug prolongers
dc.subjecthydrogels
dc.subjectgranular copolymers
dc.subjectHEMA
dc.subjectsuspension polymerization
dc.subjectpolyvinylpyrrolidone
dc.titleHydrogels in Biomedicine: Granular Controlled Release Systems Based on 2-Hydroxyethyl Methacrylate Copolymers. A Review
dc.title.alternativeГідрогелі в біомедицині: гранульні системи контрольованого вивільнення на основі (КО)полімерів 2-гідроксіетилметакрилату. Огляд
dc.typeArticle

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Chemistry & Chemical Technology. – 2024. – Vol. 18, No. 2