Validation of a method to quantify platinum in cisplatin by inductively-coupled plasma

dc.citation.epage444
dc.citation.issue4
dc.citation.spage437
dc.citation.volume11
dc.contributor.affiliationCentro de Ciencias de la Complejidad, Universidad Nacional Autónoma de México
dc.contributor.affiliationCentro de Geociencias, Universidad Nacional Autónoma de México, Campus Juriquilla
dc.contributor.affiliationLaboratorio de Neurobiologia Molecular y Celular, Instituto de Neurobiología (INB), Universidad Nacional Autónoma de México
dc.contributor.affiliationCentro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México
dc.contributor.affiliationDepartment of Materials Science and Engineering, University of North Texas
dc.contributor.authorTorres, Maykel Gonzalez
dc.contributor.authorTorres, Carolina Munoz
dc.contributor.authorTorres, Ataulfo Martinez
dc.contributor.authorMunoz, Susana Vargas
dc.contributor.authorTalavera, Rogelio Rodriguez
dc.contributor.authorRuiz-Baltazar, Alvaro de Jesus
dc.contributor.authorBrostow, Witold
dc.coverage.placenameLviv
dc.date.accessioned2018-06-22T13:26:21Z
dc.date.available2018-06-22T13:26:21Z
dc.date.created2017-01-20
dc.date.issued2017-01-20
dc.description.abstractРозглянуто можливість кількісного визна- чення цис-діаміндихлороплатини(II), відомої як цисплатин, безпосереднім застосуванням індуктивно зв’язаної плазми, зокрема визначенням концентрації платини з цисплатину у воді. Доведено, що загальна концентрація препарату може бути кількісно визначена через вміст платини з прийнятною лінійністю, чіткістю, повторюваністю, точністю, межею виявлення та межею кількісного визначення. Показана можливість застосування методу для моніторингу якості контрольних зразків для нормативного подання цисплатину та для визначення профілів вивільнення цисплатину в біомаркерних імплантатах in vitro.
dc.description.abstractCis-diaminedichloroplatinum(II), also known as cisplatin, has been quantified by use of inductivelycoupled plasma. We measured cisplatin indirectly by determining the platinum concentration in the samples. We focus on the determination of Pt from cisplatin in water. We demonstrate that the total concentration of the drug can be quantified through the content of platinum with acceptable linearity, precision, repeatability, accuracy, limit of detection and limit of quantification. Our method is applicable among others for monitoring quality of control samples for cisplatin regulatory submissions and for determination of the cisplatin release profiles in biomarker implants in vitro.
dc.format.extent437-444
dc.format.pages8
dc.identifier.citationValidation of a method to quantify platinum in cisplatin by inductively-coupled plasma / Maykel Gonzalez Torres, Carolina Munoz Torres, Ataulfo Martinez Torres, Susana Vargas Munoz, Rogelio Rodriguez Talavera, Alvaro de Jesus Ruiz-Baltazar, Witold Brostow // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2017. — Vol 11. — No 4. — P. 437–444.
dc.identifier.citationenValidation of a method to quantify platinum in cisplatin by inductively-coupled plasma / Maykel Gonzalez Torres, Carolina Munoz Torres, Ataulfo Martinez Torres, Susana Vargas Munoz, Rogelio Rodriguez Talavera, Alvaro de Jesus Ruiz-Baltazar, Witold Brostow // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2017. — Vol 11. — No 4. — P. 437–444.
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/42125
dc.language.isoen
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofChemistry & Chemical Technology, 4 (11), 2017
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dc.relation.urihttps://doi.org/10.1039/b409055a
dc.relation.urihttps://doi.org/10.1016/j.envpol.2005.11.013
dc.relation.urihttps://doi.org/10.1016/S0731-7085(00)00377-0
dc.relation.urihttps://doi.org/10.1016/j.vascn.2005.06.005
dc.relation.urihttps://doi.org/10.1016/j.sab.2007.11.029
dc.relation.urihttps://doi.org/10.1016/j.aca.2009.11.056
dc.relation.urihttps://doi.org/10.1016/j.aca.2012.09.017
dc.relation.urihttps://doi.org/10.1002/jor.1100100317
dc.relation.urihttps://doi.org/10.1002/anie.201308899
dc.relation.urihttps://doi.org/10.1016/S0378-5173(02)00382-4
dc.relation.urihttps://doi.org/10.1021/ja903300f
dc.relation.urihttps://doi.org/10.1016/S0736-0266(01)00105-X
dc.relation.urihttps://doi.org/10.1054/ijom.2000.0023
dc.relation.urihttps://doi.org/10.1371/journal.pone.0059482
dc.relation.urihttps://doi.org/10.1016/j.jcms.2016.01.012
dc.relation.urihttps://doi.org/10.1016/j.biomaterials.2015.12.016
dc.relation.urihttps://doi.org/10.1016/j.pmatsci.2015.12.001
dc.rights.holder© Національний університет „Львівська політехніка“, 2017
dc.rights.holder© Torres M., Torres C., Torres A., Muñoz S., Talavera R., Ruíz-Baltazar A., Brostow W., 2017
dc.subjectцисплатин
dc.subjectіндуційно-зв‘язана плазма
dc.subjectпрепарат від раку
dc.subjectcisplatin
dc.subjectinductively-coupled plasma
dc.subjectcancer drug
dc.titleValidation of a method to quantify platinum in cisplatin by inductively-coupled plasma
dc.title.alternativeОцінка методу квантифікації платини у цисплатині індуційно-зв’язаною плазмою
dc.typeArticle

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