Physico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates

dc.citation.epage416
dc.citation.issue4
dc.citation.spage407
dc.contributor.affiliationDDU Gorakhpur University
dc.contributor.authorSingh, Kanchan Lata
dc.contributor.authorSiddiqui, Afshan
dc.contributor.authorSingh, Kajal
dc.contributor.authorTripathi, U. N.
dc.coverage.placenameЛьвів
dc.coverage.placenameLviv
dc.date.accessioned2020-03-03T09:04:04Z
dc.date.available2020-03-03T09:04:04Z
dc.date.created2019-02-28
dc.date.issued2019-02-28
dc.description.abstractСинтезовані комплекси сурми 3(2’-гідрокси-феніл)-5-(4’-заміщений феніл)піразолінат з O,O’-алкілен дитіо-фосфатом типу [Sb (C15H12N2OX)(GO2PS2)]Cl та [Sb(C15H12N2OX)2(GO2PS2)] (де GO2PS2 – депротонований O,O’-алкілен дитіофосфат; C15H12N2OX – депротонований 3(2’-гідроксифеніл)-5-(4’-заміщений феніл)піразолінат; X = –H, –CH3,–OCH3 та –Cl; G = –C(CH3)2CH2CH(CH3)–). Проведені дослідження синтезованих сполук за допомогою елементного аналізу (C, H, N, Cl і Sb), бомбардування швидкими атомами, електронних спектральних досліджень, ІЧ-спектроскопії, багатоядерного ЯМР (1Н, 13С та 31Р). На основі одержаних даних розглянуто координацію дитіофосфату та піразолінатів, а також структуру сполук. За результатами тестів in vitro встановлено, що синтезовані комплекси мають непогану антибактеріальну та протигрибкову активність. Результати досліджень деяких зразків на активність проти папайського рингпот-вірусу, показали значну антивірусну активність з інгібуванням приблизно 34,30%.
dc.description.abstractAntimony(III) complexes of 3(2’-hydroxyphenyl)-5-(4’-substituted phenyl) pyrazolinates and O,O’-alkylene dithiophosphate of the type [Sb(C15H12N2OX) (GO2PS2)]Cl and [Sb(C15H12N2OX)2(GO2PS2)] (where GO2PS2 – deprotonated O,O’-alkylene dithiophosphate; C15H12N2OX – deprotonated 3(2'-hydroxyphenyl)-5-(4’-subsitutedphenyl) pyrazolinates; X = –H,–CH3, –OCH3 and –Cl; G = –C(CH3)2CH2CH(CH3)–) have been synthesized and characterized by elemental analysis (C, H, N, Cl and Sb), molecular weight study by FAB mass, electronic spectral studies, far and mid IR, multinuclear NMR (1H,13C and 31P). On the basis of above spectral studies, coordination of dithiophosphate and pyrazolinates along with the compounds structure have been discussed tentatively. All complexes were tested for in vitro antibacterial and antifungal activity, exhibiting a very good antibacterial and antifungal activity. Few complexes were also tested for their antiviral activity against papya ringspot virus showing a significant antiviral activity with inhibition of approximately 34.30 %.
dc.format.extent407-416
dc.format.pages10
dc.identifier.citationPhysico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates / Kanchan Lata Singh, Afshan Siddiqui, Kajal Singh, U. N. Tripathi // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2019. — Vol 13. — No 4. — P. 407–416.
dc.identifier.citationenPhysico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates / Kanchan Lata Singh, Afshan Siddiqui, Kajal Singh, U. N. Tripathi // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2019. — Vol 13. — No 4. — P. 407–416.
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/46497
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofChemistry & Chemical Technology, 4 (13), 2019
dc.relation.references1. Garji S., Jain V.: Coord. Chem. Rev., 2003, 236, 35. https://doi.org/10.1016/S0010-8545(02)00159-5
dc.relation.references2. LeeM., Gilbert H.: Infect. Med., 1999, 16, 37.
dc.relation.references3. Yu L., Ma Y-Q., Liu R-C. et al.: Polyhedron, 2004, 23, 823. https://doi.org/10.1016/j.poly.2003.12.002
dc.relation.references4. Chauhan H.: Coord. Chem. Rev., 1998, 173, 1. https://doi.org/10.1016/S0010-8545(97)00071-4
dc.relation.references5. Silvestru C., Socacia C., Bara A., Haiduc I.: J. Anticancer Res., 1990, 10, 803.
dc.relation.references6. Jung J., Watkins E., AveryM.: Hetrocycles, 2005, 65, 77. https://doi.org/10.3987/COM-04-10216
dc.relation.references7. Hamman A., Fahmy A., Amr A., Mohamad A.: Indian J. Chem., 2003, 42B, 1985.
dc.relation.references8. Braenden O., Reddy N., Habach B.: Bull. World Health Org., 1955, 13, 935.
dc.relation.references9. Soloman W., Ravi J., Annadwai K.: Indian Drugs, 1999, 36, 466.
dc.relation.references10. Bansal E., Srivastava V., Kumar A.: Eur. J. Med. Chem., 2001, 36, 81. https://doi.org/10.1016/S0223-5234(00)01179-X
dc.relation.references11. Malhotra V., Pathak S., Nath R. et al.: Indian J. Chem., 2002, 41B, 1310.
dc.relation.references12. Palasha E., Aytemir M., Uzbay I., Erol D.: Eur. J. Med. Chem., 2001, 36, 539. https://doi.org/10.1016/S0223-5234(01)01243-0
dc.relation.references13. Mastin R.: Chem. Abstr., 1983, 43, 11782.
dc.relation.references14. Shah J., Shah N.: Indian J. Chem., 1982, 21A, 312.
dc.relation.references15. Shah J., Shah N.: J. Inorg. Nucl. Chem., 1981, 43, 1593. https://doi.org/10.1016/0022-1902(81)80342-9
dc.relation.references16. Tripathi U., AhmadM., Solanki J., Bhardwaj A.: J. Coord. Chem., 2009, 62, 636. https://doi.org/10.1080/00958970802244976
dc.relation.references17. Tripathi U., Solanki J., Bhardwaj A., Thapak T.: J. Coord. Chem., 2008, 61, 4025. https://doi.org/10.1080/00958970802199964
dc.relation.references18. Tripathi U., AhmadM., Solanki J. et al.: Turkis J. Chem., 2009, 33, 257.
dc.relation.references19. Tripathi U., Venubabu G., AhmadM. et al.: J. Appl. Organomet. Chem., 2006, 20, 669. https://doi.org/10.1002/aoc.1074
dc.relation.references20. Tripathi U., AhmadM., Venubabu G., Ramakrishna P.: J. Coord. Chem., 2007, 60, 1777. https://doi.org/10.1080/00958970601183391
dc.relation.references21. Tripathi U., AhmadM., Venubabu G., Ramakrishna P.: J. Coord. Chem., 2007, 60, 1709. https://doi.org/10.1080/00958970601110865
dc.relation.references22. Tripathi U., AhmadM.:Main GroupMet. Chem., 2004, 27, 21. https://doi.org/10.1515/MGMC.2004.27.1.21
dc.relation.references23. Ratnani R., Srivastava G., Mehrotra R.: Inorg. Chem. Acta, 1989, 161, 253. https://doi.org/10.1016/S0020-1693(00)83101-1
dc.relation.references24. Vogel A.: A Text Book of Quantitative Inorganic Analysis. ELBS and Longman Group Ltd., London 1985.
dc.relation.references25. HasanM., Das R., Khan A. et al.: Adv. Biolog. Res., 2009, 3, 56.
dc.relation.references26. Mishra A., Rao G.: Phytophylactica, 1988, 20, 162.
dc.relation.references27. Tripathi U., Siddiqui A., AhmadM., Singh K.: J. Coord. Chem., 2010, 63, 894. https://doi.org/10.1080/00958971003645920
dc.relation.references28. Tripathi U., Siddiqui A., AhmadM. et al.:Main GroupMet. Chem., 2010, 33, 25. https://doi.org/10.1515/MGMC.2010.33.1-2.25
dc.relation.references29. Tripathi U., Sharma D., Jain N., Soni M.: Phosphorus Sulphur, 2007, 182, 133. https://doi.org/10.1080/10426500601091063
dc.relation.references30. Tripathi U., AhmadM., Mirza R., Siddiqui A.: Phosphorus Sulphur, 2007, 182, 1. https://doi.org/10.1080/10426500701313961
dc.relation.references31. Chauhan H., Singh U.: Appl. Organomet. Chem., 2007, 21, 880. https://doi.org/10.1002/aoc.1290
dc.relation.references32. Tripathi U., Sharma K., Chaturvedi A., Sharma T.: Polish J. Chem., 2003, 77, 109.
dc.relation.references33. Shaha N., Sau D.: Transit. Metal Chem., 2005, 30, 532. https://doi.org/10.1007/s11243-005-1029-y
dc.relation.references34. Tripathi U., Siddiqui A., AhmadM., Singh K.: J. Coord. Chem., 2010, 63, 894. https://doi.org/10.1080/00958971003645920
dc.relation.references35. Chauhan H., Singh U.: Appl. Organomet. Chem., 2007, 21, 880. https://doi.org/10.1002/aoc.1290
dc.relation.references36. Kheiri F., Tsipis C. et al.: Can. J. Chem., 1979, 57, 767. https://doi.org/10.1139/v79-125
dc.relation.referencesen1. Garji S., Jain V., Coord. Chem. Rev., 2003, 236, 35. https://doi.org/10.1016/S0010-8545(02)00159-5
dc.relation.referencesen2. LeeM., Gilbert H., Infect. Med., 1999, 16, 37.
dc.relation.referencesen3. Yu L., Ma Y-Q., Liu R-C. et al., Polyhedron, 2004, 23, 823. https://doi.org/10.1016/j.poly.2003.12.002
dc.relation.referencesen4. Chauhan H., Coord. Chem. Rev., 1998, 173, 1. https://doi.org/10.1016/S0010-8545(97)00071-4
dc.relation.referencesen5. Silvestru C., Socacia C., Bara A., Haiduc I., J. Anticancer Res., 1990, 10, 803.
dc.relation.referencesen6. Jung J., Watkins E., AveryM., Hetrocycles, 2005, 65, 77. https://doi.org/10.3987/COM-04-10216
dc.relation.referencesen7. Hamman A., Fahmy A., Amr A., Mohamad A., Indian J. Chem., 2003, 42B, 1985.
dc.relation.referencesen8. Braenden O., Reddy N., Habach B., Bull. World Health Org., 1955, 13, 935.
dc.relation.referencesen9. Soloman W., Ravi J., Annadwai K., Indian Drugs, 1999, 36, 466.
dc.relation.referencesen10. Bansal E., Srivastava V., Kumar A., Eur. J. Med. Chem., 2001, 36, 81. https://doi.org/10.1016/S0223-5234(00)01179-X
dc.relation.referencesen11. Malhotra V., Pathak S., Nath R. et al., Indian J. Chem., 2002, 41B, 1310.
dc.relation.referencesen12. Palasha E., Aytemir M., Uzbay I., Erol D., Eur. J. Med. Chem., 2001, 36, 539. https://doi.org/10.1016/S0223-5234(01)01243-0
dc.relation.referencesen13. Mastin R., Chem. Abstr., 1983, 43, 11782.
dc.relation.referencesen14. Shah J., Shah N., Indian J. Chem., 1982, 21A, 312.
dc.relation.referencesen15. Shah J., Shah N., J. Inorg. Nucl. Chem., 1981, 43, 1593. https://doi.org/10.1016/0022-1902(81)80342-9
dc.relation.referencesen16. Tripathi U., AhmadM., Solanki J., Bhardwaj A., J. Coord. Chem., 2009, 62, 636. https://doi.org/10.1080/00958970802244976
dc.relation.referencesen17. Tripathi U., Solanki J., Bhardwaj A., Thapak T., J. Coord. Chem., 2008, 61, 4025. https://doi.org/10.1080/00958970802199964
dc.relation.referencesen18. Tripathi U., AhmadM., Solanki J. et al., Turkis J. Chem., 2009, 33, 257.
dc.relation.referencesen19. Tripathi U., Venubabu G., AhmadM. et al., J. Appl. Organomet. Chem., 2006, 20, 669. https://doi.org/10.1002/aoc.1074
dc.relation.referencesen20. Tripathi U., AhmadM., Venubabu G., Ramakrishna P., J. Coord. Chem., 2007, 60, 1777. https://doi.org/10.1080/00958970601183391
dc.relation.referencesen21. Tripathi U., AhmadM., Venubabu G., Ramakrishna P., J. Coord. Chem., 2007, 60, 1709. https://doi.org/10.1080/00958970601110865
dc.relation.referencesen22. Tripathi U., AhmadM.:Main GroupMet. Chem., 2004, 27, 21. https://doi.org/10.1515/MGMC.2004.27.1.21
dc.relation.referencesen23. Ratnani R., Srivastava G., Mehrotra R., Inorg. Chem. Acta, 1989, 161, 253. https://doi.org/10.1016/S0020-1693(00)83101-1
dc.relation.referencesen24. Vogel A., A Text Book of Quantitative Inorganic Analysis. ELBS and Longman Group Ltd., London 1985.
dc.relation.referencesen25. HasanM., Das R., Khan A. et al., Adv. Biolog. Res., 2009, 3, 56.
dc.relation.referencesen26. Mishra A., Rao G., Phytophylactica, 1988, 20, 162.
dc.relation.referencesen27. Tripathi U., Siddiqui A., AhmadM., Singh K., J. Coord. Chem., 2010, 63, 894. https://doi.org/10.1080/00958971003645920
dc.relation.referencesen28. Tripathi U., Siddiqui A., AhmadM. et al.:Main GroupMet. Chem., 2010, 33, 25. https://doi.org/10.1515/MGMC.2010.33.1-2.25
dc.relation.referencesen29. Tripathi U., Sharma D., Jain N., Soni M., Phosphorus Sulphur, 2007, 182, 133. https://doi.org/10.1080/10426500601091063
dc.relation.referencesen30. Tripathi U., AhmadM., Mirza R., Siddiqui A., Phosphorus Sulphur, 2007, 182, 1. https://doi.org/10.1080/10426500701313961
dc.relation.referencesen31. Chauhan H., Singh U., Appl. Organomet. Chem., 2007, 21, 880. https://doi.org/10.1002/aoc.1290
dc.relation.referencesen32. Tripathi U., Sharma K., Chaturvedi A., Sharma T., Polish J. Chem., 2003, 77, 109.
dc.relation.referencesen33. Shaha N., Sau D., Transit. Metal Chem., 2005, 30, 532. https://doi.org/10.1007/s11243-005-1029-y
dc.relation.referencesen34. Tripathi U., Siddiqui A., AhmadM., Singh K., J. Coord. Chem., 2010, 63, 894. https://doi.org/10.1080/00958971003645920
dc.relation.referencesen35. Chauhan H., Singh U., Appl. Organomet. Chem., 2007, 21, 880. https://doi.org/10.1002/aoc.1290
dc.relation.referencesen36. Kheiri F., Tsipis C. et al., Can. J. Chem., 1979, 57, 767. https://doi.org/10.1139/v79-125
dc.relation.urihttps://doi.org/10.1016/S0010-8545(02)00159-5
dc.relation.urihttps://doi.org/10.1016/j.poly.2003.12.002
dc.relation.urihttps://doi.org/10.1016/S0010-8545(97)00071-4
dc.relation.urihttps://doi.org/10.3987/COM-04-10216
dc.relation.urihttps://doi.org/10.1016/S0223-5234(00)01179-X
dc.relation.urihttps://doi.org/10.1016/S0223-5234(01)01243-0
dc.relation.urihttps://doi.org/10.1016/0022-1902(81)80342-9
dc.relation.urihttps://doi.org/10.1080/00958970802244976
dc.relation.urihttps://doi.org/10.1080/00958970802199964
dc.relation.urihttps://doi.org/10.1002/aoc.1074
dc.relation.urihttps://doi.org/10.1080/00958970601183391
dc.relation.urihttps://doi.org/10.1080/00958970601110865
dc.relation.urihttps://doi.org/10.1515/MGMC.2004.27.1.21
dc.relation.urihttps://doi.org/10.1016/S0020-1693(00)83101-1
dc.relation.urihttps://doi.org/10.1080/00958971003645920
dc.relation.urihttps://doi.org/10.1515/MGMC.2010.33.1-2.25
dc.relation.urihttps://doi.org/10.1080/10426500601091063
dc.relation.urihttps://doi.org/10.1080/10426500701313961
dc.relation.urihttps://doi.org/10.1002/aoc.1290
dc.relation.urihttps://doi.org/10.1007/s11243-005-1029-y
dc.relation.urihttps://doi.org/10.1139/v79-125
dc.rights.holder© Національний університет „Львівська політехніка“, 2019
dc.rights.holder© Singh K.L., Siddiqui A., Singh K., Tripathi U.N., 2019
dc.subjectантибактеріальна активність
dc.subjectантивірусна активність
dc.subjectсурма(III)
dc.subjectпіразолінати
dc.subjectдитіофосфати
dc.subjectantibactirial activity
dc.subjectantiviral activity
dc.subjectantimony(III)
dc.subjectpyrazolinates
dc.subjectdithiophosphates
dc.titlePhysico-Chemical Characterization of Bioactive Mixed Ligand Complexes of Antimony with 3,5-Diarylsubstituted Pyrazolinates and O,O’-Alkylene Dithiophosphates
dc.title.alternativeФізико-хімічна характеристика біоактивних лігандних комплексів сурми з 3,5-діарилзаміщеними піразолінатами і О, О’-алкілен дітіофосфатами
dc.typeArticle

Files

Original bundle

Now showing 1 - 2 of 2
Thumbnail Image
Name:
2019v13n4_Singh_K_L-Physico_Chemical_Characterization_407-416.pdf
Size:
604.91 KB
Format:
Adobe Portable Document Format
Thumbnail Image
Name:
2019v13n4_Singh_K_L-Physico_Chemical_Characterization_407-416__COVER.png
Size:
532.04 KB
Format:
Portable Network Graphics

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.99 KB
Format:
Plain Text
Description: