A Comparative Study of the Phenolic and Flavonoids Contents, and Antioxidant Activity of Ziziphus Mauritiana’s Leaves, Ripe and Unripe Fruit Extracts from UAE

dc.citation.epage371
dc.citation.issue3
dc.citation.journalTitleХімія та хімічна технологія
dc.citation.spage363
dc.contributor.affiliationIstanbul Gelisim University
dc.contributor.affiliationUAE University
dc.contributor.authorElhaty, Ismail A.
dc.contributor.authorZeyoudi, Sendeyah A.
dc.coverage.placenameЛьвів
dc.date.accessioned2026-03-26T08:18:50Z
dc.date.created2024-02-27
dc.date.issued2024-02-27
dc.description.abstractУ цьому дослідженні оцінено антиоксидантні властивості листя, незрілих і стиглих плодів Ziziphus mauritiana з ОАЕ. Для фенольних сполук встановлено сильну кореляцію з антиоксидантною активністю, причому ефективність листя найвища. Отримані результати свідчать про те, що листя Ziziphus mauritiana є перспективним джерелом природних антиоксидантів з потенційним терапевтичним застосуванням.
dc.description.abstractThis study evaluates the antioxidant properties of leaves, unripe and ripe fruits of Ziziphus mauritiana from the UAE. Phenolic compounds show a strong correlation with antioxidant activity, with the leaves exhibiting the highest efficiency. The results suggest that Ziziphus mauritiana leaves are a promising source of natural antioxidants with potential therapeutic applications.
dc.format.extent363-371
dc.format.pages9
dc.identifier.citationElhaty I. A. A Comparative Study of the Phenolic and Flavonoids Contents, and Antioxidant Activity of Ziziphus Mauritiana’s Leaves, Ripe and Unripe Fruit Extracts from UAE / Ismail A. Elhaty, Sendeyah A. Zeyoudi // Chemistry & Chemical Technology. — Lviv Politechnic Publishing House, 2024. — Vol 18. — No 3. — P. 363–371.
dc.identifier.citationenElhaty I. A. A Comparative Study of the Phenolic and Flavonoids Contents, and Antioxidant Activity of Ziziphus Mauritiana’s Leaves, Ripe and Unripe Fruit Extracts from UAE / Ismail A. Elhaty, Sendeyah A. Zeyoudi // Chemistry & Chemical Technology. — Lviv Politechnic Publishing House, 2024. — Vol 18. — No 3. — P. 363–371.
dc.identifier.doidoi.org/10.23939/chcht18.03.363
dc.identifier.urihttps://ena.lpnu.ua/handle/ntb/124827
dc.language.isoen
dc.publisherВидавництво Львівської політехніки
dc.publisherLviv Politechnic Publishing House
dc.relation.ispartofХімія та хімічна технологія, 3 (18), 2024
dc.relation.ispartofChemistry & Chemical Technology, 3 (18), 2024
dc.relation.references[1] Aruoma, O. I. Free Radicals, Antioxidants and International Nutrition. Asia Pacific Journal of Clinical Nutrition 1999, 8, 53–63. http://dx.doi.org/10.1046/j.1440-6047.1999.00036.x
dc.relation.references[2] Gupta, V. K.; Sharma, S. K. Plants as Natural Antioxidants. Nat Prod Radiance 2006, 5, 326–334.
dc.relation.references[3] Magder, S. Reactive Oxygen Species: Toxic Molecules or Spark of Life? Crit Care 2006, 10, 208. https://doi.org/10.1186/cc3992
dc.relation.references[4] Burlakova, E.; Molochkina, E.; Nikiforov, G. Hybrid Antioxidants. Chem. Chem. Technol. 2008, 2, 163–171. https://doi.org/10.23939/chcht02.03.163
dc.relation.references[5] Halliwell, B. How to Characterize an Antioxidant: An Update. Biochem Soc Symp 1995, 61, 73–101. https://doi.org/10.1042/bss0610073
dc.relation.references[6] Skiba, M.; Zaporozhets, J. Antioxidant Activity and Phytochemical Screening of the Apricot Cake Extract: Experimental and Theoretical Studies. Chem. Chem. Technol. 2022, 16, 591–599. https://doi.org/10.23939/chcht16.04.591
dc.relation.references[7] Sazhina, N.; Misin, V. M.; Korotkova, E. I. Study of Mint Extracts Antioxidant Activity by Electrochemical Methods. Chem. Chem. Technol. 2011, 5, 13–17. https://doi.org/10.23939/chcht05.01.013
dc.relation.references[8] Brewer, M. S. Natural Antioxidants: Sources, Compounds, Mechanisms of Action, and Potential Applications. Compr. Rev. Food Sci. Food Saf 2011, 10, 221–247. http://dx.doi.org/10.1111/j.1541-4337.2011.00156.x
dc.relation.references[9] Soobrattee, M. A.; Neergheen, V. S.; Luximon-Ramma, A.; Aruoma, O. I.; Bahorun, T. Phenolics as Potential Antioxidant Therapeutic Agents: Mechanism and Actions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2005, 579, 200–213.https://doi.org/10.1016/j.mrfmmm.2005.03.023
dc.relation.references[10] Chaudière, J.; Ferrari-Iliou, R. Intracellular Antioxidants: from Chemical to Biochemical Mechanisms. Food Chem. Toxicol. 1999, 37, 949–962. https://doi.org/10.1016/s0278-6915(99)00090-3
dc.relation.references[11] Akbari, B.; Baghaei-Yazdi, N.; Bahmaie, M.; Mahdavi Abhari, F. The Role of Plant-Derived Natural Antioxidants in Reduction of Oxidative Stress. BioFactors 2022, 48, 611–633. https://doi.org/10.1002/biof.1831
dc.relation.references[12] Hinneburg, I.; Damien Dorman, H. J.; Hiltunen, R. Antioxidant Activities of Extracts from Selected Culinary Herbs and Spices. Food Chem 2006, 97, 122–129. https://doi.org/10.1016/j.foodchem.2005.03.028
dc.relation.references[13] Liu, R. H. Health Benefits of Fruit and Vegetables are from Additive and Synergistic Combinations of Phytochemicals. The American journal of clinical nutrition 2003, 78, 517s–520s. https://doi.org/10.1093/ajcn/78.3.517S
dc.relation.references[14] Al-Dabbagh, B.; Elhaty, I. A.; Al Hrout, A. a.; Al Sakkaf, R.; El-Awady, R.; Ashraf, S. S.; Amin, A. Antioxidant and Anticancer Activities of Trigonella foenum-graecum, Cassia acutifolia and Rhazya stricta. BMC Complementary and Alternative Medicine 2018, 18, 240–252. https://doi.org/10.1186/s12906-018-2285-7
dc.relation.references[15] Al-Dabbagh, B.; Elhaty, I. A.; Elhaw, M.; Murali, C.; Al Mansoori, A.; Awad, B.; Amin, A. Antioxidant and Anticancer Activities of Chamomile (Matricaria recutita L.). BMC Res. Notes 2019, 12, 3. https://doi.org/10.1186/s13104-018-3960-y
dc.relation.references[16] Al-Dabbagh, B.; Elhaty, I. A.; Murali, C.; Madhoon, A. A.; Amin, A. Salvadora persica (Miswak): Antioxidant and Promising Antiangiogenic Insights. American Journal of Plant Sciences 2018, 09, 1228–1244. https://doi.org/10.4236/ajps.2018.96091
dc.relation.references[17] Koehn, F. E.; Carter, G. T. The Evolving Role of Natural Products in Drug Discovery. Nat. Rev. Drug Discovery 2005, 4, 206. https://doi.org/10.1038/nrd1657
dc.relation.references[18] Way, T.-D.; Kao, M.-C.; Lin, J.-K. Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-Overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway. J. Biol. Chem. 2004, 279, 4479–4489.https://doi.org/10.1074/jbc.m305529200
dc.relation.references[19] Patel, D.; Shukla, S.; Gupta, S. Apigenin and Cancer Chemoprevention: Progress, Potential and Promise (Review). Int. J. Oncol. 2007, 30, 233–245. https://doi.org/10.3892/ijo.30.1.233
dc.relation.references[20] Memon, A. A.; Memon, N.; Bhanger, M. I.; Luthria, D. L. Assay of Phenolic Compounds from four Species of ber (Ziziphus mauritiana L.) Fruits: Comparison of Three Base Hydrolysis Procedure for Quantification of Total Phenolic Acids. Food Chem2013, 139, 496–502.https://doi.org/10.1016/j.foodchem.2013.01.065
dc.relation.references[21] Cacciola, A.; D'Angelo, V.; Raimondo, F. M.; Germanò, M. P.; Braca, A.; De Leo, M. Ziziphus lotus (L.) Lam. as a Source of Health Promoting Products: Metabolomic Profile, Antioxidant and Tyrosinase Inhibitory Activities. Chemistry & Biodiversity 2022, 19, e202200237. https://doi.org/10.1002/cbdv.202200237
dc.relation.references[22] Ezz, T. M.; Yousif, A. M.; Farag, M. E. Morphological, Physiological and Biochemical Genetic Studies on Some Indian Jujube (Ziziphus mauritiana Lamk.) Varieties Grown at El Nubaria. Egyptian Journal of Agricultural Research 2011, 89, 1499–1525. http://dx.doi.org/10.21608/ejar.2011.179481
dc.relation.references[23] Anjum, M. A.; Haram, A.; Ahmad, R.; Bashir, M. A. Physico- Chemical Attributes of Fresh and Dried Indian Jujube (Zizyphus Mauritiana) Fruits. Pak. J. Agri. Sci. 2020, 57, 165–176. https://doi.org/10.21162/PAKJAS/20.7845
dc.relation.references[24] Gupta, M.; Bhandari, A.; Singh, R. K. Pharmacognostical Evaluations of the Leaves of Ziziphus mauritiana. Int. J. Pharm. Sci. Res. 2012, 3, 818. http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).818-21
dc.relation.references[25] Dahiru, D.; Obidoa, O. Pretreatment of Albino Rats with Aqueous Leaf Extract of Ziziphus mauritiana Protects against Alcohol-Induced Liver Damage. Trop. J. Pharm. Res. 2007, 6, 705– 710. https://doi.org/10.4314/tjpr.v6i2.14649
dc.relation.references[26] Zozio, S.; Servent, A.; Cazal, G.; Mbéguié-A-Mbéguié, D.; Ravion, S.; Pallet, D.; Abel, H. Changes in Antioxidant Activity during the Ripening of Jujube (Ziziphus mauritiana Lamk). Food Chem 2014, 150, 448–456.https://doi.org/10.1016/j.foodchem.2013.11.022
dc.relation.references[27] Bhatia, A.; Mishra, T. Free Radical Scavenging and Antioxidant Potential of Ziziphus mauritiana (Lamk.) Seed Extract. Journal of Complementary and Integrative Medicine 2009, 8, 42–46. https://doi.org/10.2202/1553-3840.1214
dc.relation.references[28] Vahedi, F.; Najafi, M. F.; Bozari, K. Evaluation of Inhibitory Effect and Apoptosis Induction of Zyzyphus Jujube on Tumor Cell Lines, an in vitro Preliminary Study. Cytotechnology 2008, 56, 105– 111. https://doi.org/10.1007%2Fs10616-008-9131-6
dc.relation.references[29] Akanda, M. K. M.; Hasan, A. H. M. N. Characterization of Pharmacological Properties of Methanolic Seed and Stem Bark Extracts of Ziziphus mauritiana (BAU Kul) Using in-vitro and in- vivo Animal (Swiss albino male mice) Model. Clin. Phytosci. 2021, 7, 8. https://doi.org/10.1186/s40816-020-00246-0
dc.relation.references[30] Aldhanhani, A. R.; Ahmed, Z. F.; Tzortzakis, N.; Singh, Z. Maturity Stage at Harvest Influences Antioxidant Phytochemicals and Antibacterial Activity of Jujube Fruit (Ziziphus mauritiana Lamk. and Ziziphus spina-christi L.). Ann. Agric. Sci. 2022, 67, 196–203. https://doi.org/10.1016/j.aoas.2022.12.003
dc.relation.references[31] Owolarafe, T. A.; Salawu, K.; Ihegboro, G. O.; Ononamadu, C. J.; Alhassan, A. J.; Wudil, A. M. Investigation of Cytotoxicity Potential of Different Extracts of Ziziphus mauritiana (Lam) Leaf Allium cepa Model. Toxicol. Rep. 2020, 7, 816–821. https://doi.org/10.1016/j.toxrep.2020.06.010
dc.relation.references[32] Jain, P.; Haque, A.; Islam, T.; Alam, M. A.; Reza, H. M. Comparative Evaluation of Ziziphus mauritiana Leaf Extracts for Phenolic Content, Antioxidant and Antibacterial Activities. Journal of Herbs, Spices & Medicinal Plants 2019, 25, 236–258. https://doi.org/10.1080/10496475.2019.1600627
dc.relation.references[33] Singleton, V. L.; Orthofer, R.; Lamuela-Raventós, R. M.. Analysis of Total Phenols and Other Oxidation Substrates and Antioxidants by Means of Folin-Ciocalteu Reagent. In Methods in Enzymology, Vol. 299; Academic Press, 1999; pp 152–178.
dc.relation.references[34] Al-Saeedi, A. H.; Al- Ghafri, M. T. H.; Hossain, M. A. Comparative Evaluation of total Phenols, Flavonoids Content and Antioxidant Potential of Leaf and Fruit Extracts of Omani Ziziphus Jujuba L. Pac. Sci. Rev. A: Nat. Sci. Eng. 2016, 18, 78–83. https://doi.org/10.1016/j.psra.2016.09.001
dc.relation.references[35] Chang, C.-C.; Yang, M.-H.; Wen, H.-M.; Chern, J.-C. Estimation of Total Flavonoid Content in Propolis by Two Complementary Colorimetric Methods. Journal of Food Drug Analysis 2002, 10, 178–182. https://doi.org/10.38212/2224-6614.2748
dc.relation.references[36] Lim, Y. Y.; Quah, E. P. L. Antioxidant Properties of Different Cultivars of Portulaca oleracea. Food Chem 2007, 103, 734–740. https://doi.org/10.1016/j.foodchem.2006.09.025
dc.relation.references[37] Chen, Z.; Bertin, R.; Froldi, G. EC50 Estimation of Antioxidant Activity in DPPH Assay using Several Statistical Programs. Food Chem 2013, 138, 414–420. https://doi.org/10.1016/j.foodchem.2012.11.001
dc.relation.references[38] Roby, M. H. H.; Sarhan, M. A.; Selim, K. A.-H.; Khalel, K. I. Antioxidant and Antimicrobial Activities of Essential Oil and Extracts of Fennel (Foeniculum vulgare L.) and chamomile (Matricaria chamomilla L.). Ind. Crops Prod. 2013, 44, 437–445. http://doi.org/10.1016/j.indcrop.2012.10.012
dc.relation.references[39] Robbins, R. J. Phenolic Acids in Foods: An Overview of Analytical Methodology. J Agric Food Chem 2003, 51, 2866–2887. https://doi.org/10.1021/jf026182t
dc.relation.references[40] Wojdyło, A.; Oszmiański, J.; Czemerys, R. Antioxidant Activity and Phenolic Compounds in 32 Selected Herbs. Food Chem 2007, 105, 940–949.https://doi.org/10.1016/j.foodchem.2007.04.038
dc.relation.references[41] Pontis, J. A.; Costa, L. A. M. A. d.; Silva, S. J. R. d.; Flach, A. Color, Phenolic and Flavonoid Content, and Antioxidant Activity of Honey from Roraima, Brazil. Food Science and Technology (Campinas) 2014, 34, 69–73. http://dx.doi.org/10.1590/S0101-20612014005000015
dc.relation.references[42] Yan, M.; Wang, Y.; Watharkar, R. B.; Pu, Y.; Wu, C.; Lin, M.; Lu, D.; Liu, M.; Bao, J.; Xia, Y. Physicochemical and Antioxidant Activity of Fruit Harvested from Eight Jujube (Ziziphus jujuba Mill.) Cultivars at Different Development Stages. Sci. Rep. 2022, 12, 2272. https://doi.org/10.1038/s41598-022-06313-5
dc.relation.references[43] Gao, Q. H.; Wu, C. S.; Yu, J. G.; Wang, M.; Ma, Y. J.; Li, C. L. Textural Characteristic, Antioxidant Activity, Sugar, Organic Acid, and Phenolic Profiles of 10 Promising Jujube (Ziziphus jujuba Mill.) Selections. J. Food Sci. 2012, 77, C1218–25. https://doi.org/10.1111/j.1750-3841.2012.02946.x
dc.relation.references[44] Wojdyło, A.; Carbonell-Barrachina, Á. A.; Legua, P.; Hernández, F. Phenolic Composition, Ascorbic Acid Content, and Antioxidant Capacity of Spanish Jujube (Ziziphus jujube Mill.) Fruits. Food Chem 2016, 201, 307–314. https://doi.org/10.1016/j.foodchem.2016.01.090
dc.relation.references[45] Gao, Q.-H.; Wu, P.-T.; Liu, J.-R.; Wu, C.-S.; Parry, J. W.;Wang, M. Physico-Chemical Properties and Antioxidant Capacity of Different Jujube (Ziziphus jujuba Mill.) Cultivars Grown in Loess Plateau of China. Sci. Hortic. 2011, 130, 67–72. https://doi.org/10.1016/j.scienta.2011.06.005
dc.relation.references[46] Wang, B.-N.; Cao, W.; Gao, H.; Fan, M.-T.; Zheng, J.-B. Simultaneous Determination of Six Phenolic Compounds in Jujube by LC-ECD. Chromatographia 2010, 71, 703–707. https://doi.org/10.1365/s10337-010-1485-1
dc.relation.references[47] Gao, Q.-H.; Wu, C.-S.; Wang, M. The Jujube (Ziziphus Jujuba Mill.) Fruit: A Review of Current Knowledge of Fruit Composition and Health Benefits. J Agric Food Chem 2013, 61, 3351–3363. https://doi.org/10.1021/jf4007032
dc.relation.references[48] Xue, X.; Zhao, A.; Wang, Y.; Ren, H.; Du, J.; Li, D.; Li, Y. Composition and Content of Phenolic Acids and Flavonoids Among the Different Varieties, Development Stages, and Tissues of ChineseJujube (Ziziphus jujuba Mill.). PloS one 2021, 16, e0254058. https://doi.org/10.1371/journal.pone.0254058
dc.relation.references[49] Shan, B.; Cai, Y. Z.; Sun, M.; Corke, H. Antioxidant Capacity of 26 Spice Extracts and Characterization of their Phenolic Constituents. J Agric Food Chem 2005, 53, 7749–7759. https://doi.org/10.1021/jf051513y
dc.relation.references[50] Amin, A.; Mousa, M. Merits of Anti-Cancer Plants from the Arabian Gulf Region. Cancer Therapy 2007, 5, 55–66.
dc.relation.references[51] Popova, M.; Bankova, V.; Butovska, D.; Petkov, V.; Nikolova- Damyanova, B.; Sabatini, A. G.; Marcazzan, G. L.; Bogdanov, S. Validated Methods for the Quantification of Biologically Active Constituents of Poplar-Type Propolis. Phytochem Anal 2004, 15, 235–240. https://doi.org/10.1002/pca.777
dc.relation.references[52] Capocasa, F.; Scalzo, J.; Mezzetti, B.; Battino, M. Combining Quality and Antioxidant Attributes in the Strawberry: The Role of Genotype. Food Chem 2008, 111, 872–878. https://doi.org/10.1016/j.foodchem.2008.04.068
dc.relation.references[53] Robards, K.; Prenzler, P. D.; Tucker, G.; Swatsitang, P.; Glover, W. Phenolic Compounds and their Role in Oxidative Processes in Fruits. Food Chem 1999, 66, 401–436. https://doi.org/10.1016/S0308-8146(99)00093-X
dc.relation.references[54] Kitts, D. D.; Wijewickreme, A. N.; Hu, C. Antioxidant Properties of a North American Ginseng Extract. Mol Cell Biochem 2000, 203, 1–10. https://doi.org/10.1023/a:1007078414639
dc.relation.references[55] Fettah, A.; Hachani, S. E.; Chennai, Y.; Zeghdoud , H. Phytochemical Screening, Antibacterial and Antioxidant Activities of Ocimum basilicum L. Cultivated in Biskra, Algeria. Chem.Chem. Technol. 2023, 17, 397–406. https://doi.org/10.23939/chcht17.02.397
dc.relation.references[56] Wang, B.; Huang, Q.; Venkitasamy, C.; Chai, H.; Gao, H.; Cheng, N.; Cao, W.; Lv, X.; Pan, Z. Changes in Phenolic Compounds and their Antioxidant Capacities in Jujube (Ziziphus jujuba Miller) during Three Edible Maturity Stages. LWT-Food Science and Technology 2016, 66, 56–62. https://doi.org/10.1016/j.lwt.2015.10.005
dc.relation.referencesen[1] Aruoma, O. I. Free Radicals, Antioxidants and International Nutrition. Asia Pacific Journal of Clinical Nutrition 1999, 8, 53–63. http://dx.doi.org/10.1046/j.1440-6047.1999.00036.x
dc.relation.referencesen[2] Gupta, V. K.; Sharma, S. K. Plants as Natural Antioxidants. Nat Prod Radiance 2006, 5, 326–334.
dc.relation.referencesen[3] Magder, S. Reactive Oxygen Species: Toxic Molecules or Spark of Life? Crit Care 2006, 10, 208. https://doi.org/10.1186/cc3992
dc.relation.referencesen[4] Burlakova, E.; Molochkina, E.; Nikiforov, G. Hybrid Antioxidants. Chem. Chem. Technol. 2008, 2, 163–171. https://doi.org/10.23939/chcht02.03.163
dc.relation.referencesen[5] Halliwell, B. How to Characterize an Antioxidant: An Update. Biochem Soc Symp 1995, 61, 73–101. https://doi.org/10.1042/bss0610073
dc.relation.referencesen[6] Skiba, M.; Zaporozhets, J. Antioxidant Activity and Phytochemical Screening of the Apricot Cake Extract: Experimental and Theoretical Studies. Chem. Chem. Technol. 2022, 16, 591–599. https://doi.org/10.23939/chcht16.04.591
dc.relation.referencesen[7] Sazhina, N.; Misin, V. M.; Korotkova, E. I. Study of Mint Extracts Antioxidant Activity by Electrochemical Methods. Chem. Chem. Technol. 2011, 5, 13–17. https://doi.org/10.23939/chcht05.01.013
dc.relation.referencesen[8] Brewer, M. S. Natural Antioxidants: Sources, Compounds, Mechanisms of Action, and Potential Applications. Compr. Rev. Food Sci. Food Saf 2011, 10, 221–247. http://dx.doi.org/10.1111/j.1541-4337.2011.00156.x
dc.relation.referencesen[9] Soobrattee, M. A.; Neergheen, V. S.; Luximon-Ramma, A.; Aruoma, O. I.; Bahorun, T. Phenolics as Potential Antioxidant Therapeutic Agents: Mechanism and Actions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2005, 579, 200–213.https://doi.org/10.1016/j.mrfmmm.2005.03.023
dc.relation.referencesen[10] Chaudière, J.; Ferrari-Iliou, R. Intracellular Antioxidants: from Chemical to Biochemical Mechanisms. Food Chem. Toxicol. 1999, 37, 949–962. https://doi.org/10.1016/s0278-6915(99)00090-3
dc.relation.referencesen[11] Akbari, B.; Baghaei-Yazdi, N.; Bahmaie, M.; Mahdavi Abhari, F. The Role of Plant-Derived Natural Antioxidants in Reduction of Oxidative Stress. BioFactors 2022, 48, 611–633. https://doi.org/10.1002/biof.1831
dc.relation.referencesen[12] Hinneburg, I.; Damien Dorman, H. J.; Hiltunen, R. Antioxidant Activities of Extracts from Selected Culinary Herbs and Spices. Food Chem 2006, 97, 122–129. https://doi.org/10.1016/j.foodchem.2005.03.028
dc.relation.referencesen[13] Liu, R. H. Health Benefits of Fruit and Vegetables are from Additive and Synergistic Combinations of Phytochemicals. The American journal of clinical nutrition 2003, 78, 517s–520s. https://doi.org/10.1093/ajcn/78.3.517S
dc.relation.referencesen[14] Al-Dabbagh, B.; Elhaty, I. A.; Al Hrout, A. a.; Al Sakkaf, R.; El-Awady, R.; Ashraf, S. S.; Amin, A. Antioxidant and Anticancer Activities of Trigonella foenum-graecum, Cassia acutifolia and Rhazya stricta. BMC Complementary and Alternative Medicine 2018, 18, 240–252. https://doi.org/10.1186/s12906-018-2285-7
dc.relation.referencesen[15] Al-Dabbagh, B.; Elhaty, I. A.; Elhaw, M.; Murali, C.; Al Mansoori, A.; Awad, B.; Amin, A. Antioxidant and Anticancer Activities of Chamomile (Matricaria recutita L.). BMC Res. Notes 2019, 12, 3. https://doi.org/10.1186/s13104-018-3960-y
dc.relation.referencesen[16] Al-Dabbagh, B.; Elhaty, I. A.; Murali, C.; Madhoon, A. A.; Amin, A. Salvadora persica (Miswak): Antioxidant and Promising Antiangiogenic Insights. American Journal of Plant Sciences 2018, 09, 1228–1244. https://doi.org/10.4236/ajps.2018.96091
dc.relation.referencesen[17] Koehn, F. E.; Carter, G. T. The Evolving Role of Natural Products in Drug Discovery. Nat. Rev. Drug Discovery 2005, 4, 206. https://doi.org/10.1038/nrd1657
dc.relation.referencesen[18] Way, T.-D.; Kao, M.-C.; Lin, J.-K. Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-Overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway. J. Biol. Chem. 2004, 279, 4479–4489.https://doi.org/10.1074/jbc.m305529200
dc.relation.referencesen[19] Patel, D.; Shukla, S.; Gupta, S. Apigenin and Cancer Chemoprevention: Progress, Potential and Promise (Review). Int. J. Oncol. 2007, 30, 233–245. https://doi.org/10.3892/ijo.30.1.233
dc.relation.referencesen[20] Memon, A. A.; Memon, N.; Bhanger, M. I.; Luthria, D. L. Assay of Phenolic Compounds from four Species of ber (Ziziphus mauritiana L.) Fruits: Comparison of Three Base Hydrolysis Procedure for Quantification of Total Phenolic Acids. Food Chem2013, 139, 496–502.https://doi.org/10.1016/j.foodchem.2013.01.065
dc.relation.referencesen[21] Cacciola, A.; D'Angelo, V.; Raimondo, F. M.; Germanò, M. P.; Braca, A.; De Leo, M. Ziziphus lotus (L.) Lam. as a Source of Health Promoting Products: Metabolomic Profile, Antioxidant and Tyrosinase Inhibitory Activities. Chemistry & Biodiversity 2022, 19, e202200237. https://doi.org/10.1002/cbdv.202200237
dc.relation.referencesen[22] Ezz, T. M.; Yousif, A. M.; Farag, M. E. Morphological, Physiological and Biochemical Genetic Studies on Some Indian Jujube (Ziziphus mauritiana Lamk.) Varieties Grown at El Nubaria. Egyptian Journal of Agricultural Research 2011, 89, 1499–1525. http://dx.doi.org/10.21608/ejar.2011.179481
dc.relation.referencesen[23] Anjum, M. A.; Haram, A.; Ahmad, R.; Bashir, M. A. Physico- Chemical Attributes of Fresh and Dried Indian Jujube (Zizyphus Mauritiana) Fruits. Pak. J. Agri. Sci. 2020, 57, 165–176. https://doi.org/10.21162/PAKJAS/20.7845
dc.relation.referencesen[24] Gupta, M.; Bhandari, A.; Singh, R. K. Pharmacognostical Evaluations of the Leaves of Ziziphus mauritiana. Int. J. Pharm. Sci. Res. 2012, 3, 818. http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).818-21
dc.relation.referencesen[25] Dahiru, D.; Obidoa, O. Pretreatment of Albino Rats with Aqueous Leaf Extract of Ziziphus mauritiana Protects against Alcohol-Induced Liver Damage. Trop. J. Pharm. Res. 2007, 6, 705– 710. https://doi.org/10.4314/tjpr.v6i2.14649
dc.relation.referencesen[26] Zozio, S.; Servent, A.; Cazal, G.; Mbéguié-A-Mbéguié, D.; Ravion, S.; Pallet, D.; Abel, H. Changes in Antioxidant Activity during the Ripening of Jujube (Ziziphus mauritiana Lamk). Food Chem 2014, 150, 448–456.https://doi.org/10.1016/j.foodchem.2013.11.022
dc.relation.referencesen[27] Bhatia, A.; Mishra, T. Free Radical Scavenging and Antioxidant Potential of Ziziphus mauritiana (Lamk.) Seed Extract. Journal of Complementary and Integrative Medicine 2009, 8, 42–46. https://doi.org/10.2202/1553-3840.1214
dc.relation.referencesen[28] Vahedi, F.; Najafi, M. F.; Bozari, K. Evaluation of Inhibitory Effect and Apoptosis Induction of Zyzyphus Jujube on Tumor Cell Lines, an in vitro Preliminary Study. Cytotechnology 2008, 56, 105– 111. https://doi.org/10.1007%2Fs10616-008-9131-6
dc.relation.referencesen[29] Akanda, M. K. M.; Hasan, A. H. M. N. Characterization of Pharmacological Properties of Methanolic Seed and Stem Bark Extracts of Ziziphus mauritiana (BAU Kul) Using in-vitro and in- vivo Animal (Swiss albino male mice) Model. Clin. Phytosci. 2021, 7, 8. https://doi.org/10.1186/s40816-020-00246-0
dc.relation.referencesen[30] Aldhanhani, A. R.; Ahmed, Z. F.; Tzortzakis, N.; Singh, Z. Maturity Stage at Harvest Influences Antioxidant Phytochemicals and Antibacterial Activity of Jujube Fruit (Ziziphus mauritiana Lamk. and Ziziphus spina-christi L.). Ann. Agric. Sci. 2022, 67, 196–203. https://doi.org/10.1016/j.aoas.2022.12.003
dc.relation.referencesen[31] Owolarafe, T. A.; Salawu, K.; Ihegboro, G. O.; Ononamadu, C. J.; Alhassan, A. J.; Wudil, A. M. Investigation of Cytotoxicity Potential of Different Extracts of Ziziphus mauritiana (Lam) Leaf Allium cepa Model. Toxicol. Rep. 2020, 7, 816–821. https://doi.org/10.1016/j.toxrep.2020.06.010
dc.relation.referencesen[32] Jain, P.; Haque, A.; Islam, T.; Alam, M. A.; Reza, H. M. Comparative Evaluation of Ziziphus mauritiana Leaf Extracts for Phenolic Content, Antioxidant and Antibacterial Activities. Journal of Herbs, Spices & Medicinal Plants 2019, 25, 236–258. https://doi.org/10.1080/10496475.2019.1600627
dc.relation.referencesen[33] Singleton, V. L.; Orthofer, R.; Lamuela-Raventós, R. M.. Analysis of Total Phenols and Other Oxidation Substrates and Antioxidants by Means of Folin-Ciocalteu Reagent. In Methods in Enzymology, Vol. 299; Academic Press, 1999; pp 152–178.
dc.relation.referencesen[34] Al-Saeedi, A. H.; Al- Ghafri, M. T. H.; Hossain, M. A. Comparative Evaluation of total Phenols, Flavonoids Content and Antioxidant Potential of Leaf and Fruit Extracts of Omani Ziziphus Jujuba L. Pac. Sci. Rev. A: Nat. Sci. Eng. 2016, 18, 78–83. https://doi.org/10.1016/j.psra.2016.09.001
dc.relation.referencesen[35] Chang, C.-C.; Yang, M.-H.; Wen, H.-M.; Chern, J.-C. Estimation of Total Flavonoid Content in Propolis by Two Complementary Colorimetric Methods. Journal of Food Drug Analysis 2002, 10, 178–182. https://doi.org/10.38212/2224-6614.2748
dc.relation.referencesen[36] Lim, Y. Y.; Quah, E. P. L. Antioxidant Properties of Different Cultivars of Portulaca oleracea. Food Chem 2007, 103, 734–740. https://doi.org/10.1016/j.foodchem.2006.09.025
dc.relation.referencesen[37] Chen, Z.; Bertin, R.; Froldi, G. EC50 Estimation of Antioxidant Activity in DPPH Assay using Several Statistical Programs. Food Chem 2013, 138, 414–420. https://doi.org/10.1016/j.foodchem.2012.11.001
dc.relation.referencesen[38] Roby, M. H. H.; Sarhan, M. A.; Selim, K. A.-H.; Khalel, K. I. Antioxidant and Antimicrobial Activities of Essential Oil and Extracts of Fennel (Foeniculum vulgare L.) and chamomile (Matricaria chamomilla L.). Ind. Crops Prod. 2013, 44, 437–445. http://doi.org/10.1016/j.indcrop.2012.10.012
dc.relation.referencesen[39] Robbins, R. J. Phenolic Acids in Foods: An Overview of Analytical Methodology. J Agric Food Chem 2003, 51, 2866–2887. https://doi.org/10.1021/jf026182t
dc.relation.referencesen[40] Wojdyło, A.; Oszmiański, J.; Czemerys, R. Antioxidant Activity and Phenolic Compounds in 32 Selected Herbs. Food Chem 2007, 105, 940–949.https://doi.org/10.1016/j.foodchem.2007.04.038
dc.relation.referencesen[41] Pontis, J. A.; Costa, L. A. M. A. d.; Silva, S. J. R. d.; Flach, A. Color, Phenolic and Flavonoid Content, and Antioxidant Activity of Honey from Roraima, Brazil. Food Science and Technology (Campinas) 2014, 34, 69–73. http://dx.doi.org/10.1590/S0101-20612014005000015
dc.relation.referencesen[42] Yan, M.; Wang, Y.; Watharkar, R. B.; Pu, Y.; Wu, C.; Lin, M.; Lu, D.; Liu, M.; Bao, J.; Xia, Y. Physicochemical and Antioxidant Activity of Fruit Harvested from Eight Jujube (Ziziphus jujuba Mill.) Cultivars at Different Development Stages. Sci. Rep. 2022, 12, 2272. https://doi.org/10.1038/s41598-022-06313-5
dc.relation.referencesen[43] Gao, Q. H.; Wu, C. S.; Yu, J. G.; Wang, M.; Ma, Y. J.; Li, C. L. Textural Characteristic, Antioxidant Activity, Sugar, Organic Acid, and Phenolic Profiles of 10 Promising Jujube (Ziziphus jujuba Mill.) Selections. J. Food Sci. 2012, 77, P.1218–25. https://doi.org/10.1111/j.1750-3841.2012.02946.x
dc.relation.referencesen[44] Wojdyło, A.; Carbonell-Barrachina, Á. A.; Legua, P.; Hernández, F. Phenolic Composition, Ascorbic Acid Content, and Antioxidant Capacity of Spanish Jujube (Ziziphus jujube Mill.) Fruits. Food Chem 2016, 201, 307–314. https://doi.org/10.1016/j.foodchem.2016.01.090
dc.relation.referencesen[45] Gao, Q.-H.; Wu, P.-T.; Liu, J.-R.; Wu, C.-S.; Parry, J. W.;Wang, M. Physico-Chemical Properties and Antioxidant Capacity of Different Jujube (Ziziphus jujuba Mill.) Cultivars Grown in Loess Plateau of China. Sci. Hortic. 2011, 130, 67–72. https://doi.org/10.1016/j.scienta.2011.06.005
dc.relation.referencesen[46] Wang, B.-N.; Cao, W.; Gao, H.; Fan, M.-T.; Zheng, J.-B. Simultaneous Determination of Six Phenolic Compounds in Jujube by LC-ECD. Chromatographia 2010, 71, 703–707. https://doi.org/10.1365/s10337-010-1485-1
dc.relation.referencesen[47] Gao, Q.-H.; Wu, C.-S.; Wang, M. The Jujube (Ziziphus Jujuba Mill.) Fruit: A Review of Current Knowledge of Fruit Composition and Health Benefits. J Agric Food Chem 2013, 61, 3351–3363. https://doi.org/10.1021/jf4007032
dc.relation.referencesen[48] Xue, X.; Zhao, A.; Wang, Y.; Ren, H.; Du, J.; Li, D.; Li, Y. Composition and Content of Phenolic Acids and Flavonoids Among the Different Varieties, Development Stages, and Tissues of ChineseJujube (Ziziphus jujuba Mill.). PloS one 2021, 16, e0254058. https://doi.org/10.1371/journal.pone.0254058
dc.relation.referencesen[49] Shan, B.; Cai, Y. Z.; Sun, M.; Corke, H. Antioxidant Capacity of 26 Spice Extracts and Characterization of their Phenolic Constituents. J Agric Food Chem 2005, 53, 7749–7759. https://doi.org/10.1021/jf051513y
dc.relation.referencesen[50] Amin, A.; Mousa, M. Merits of Anti-Cancer Plants from the Arabian Gulf Region. Cancer Therapy 2007, 5, 55–66.
dc.relation.referencesen[51] Popova, M.; Bankova, V.; Butovska, D.; Petkov, V.; Nikolova- Damyanova, B.; Sabatini, A. G.; Marcazzan, G. L.; Bogdanov, S. Validated Methods for the Quantification of Biologically Active Constituents of Poplar-Type Propolis. Phytochem Anal 2004, 15, 235–240. https://doi.org/10.1002/pca.777
dc.relation.referencesen[52] Capocasa, F.; Scalzo, J.; Mezzetti, B.; Battino, M. Combining Quality and Antioxidant Attributes in the Strawberry: The Role of Genotype. Food Chem 2008, 111, 872–878. https://doi.org/10.1016/j.foodchem.2008.04.068
dc.relation.referencesen[53] Robards, K.; Prenzler, P. D.; Tucker, G.; Swatsitang, P.; Glover, W. Phenolic Compounds and their Role in Oxidative Processes in Fruits. Food Chem 1999, 66, 401–436. https://doi.org/10.1016/S0308-8146(99)00093-X
dc.relation.referencesen[54] Kitts, D. D.; Wijewickreme, A. N.; Hu, C. Antioxidant Properties of a North American Ginseng Extract. Mol Cell Biochem 2000, 203, 1–10. https://doi.org/10.1023/a:1007078414639
dc.relation.referencesen[55] Fettah, A.; Hachani, S. E.; Chennai, Y.; Zeghdoud , H. Phytochemical Screening, Antibacterial and Antioxidant Activities of Ocimum basilicum L. Cultivated in Biskra, Algeria. Chem.Chem. Technol. 2023, 17, 397–406. https://doi.org/10.23939/chcht17.02.397
dc.relation.referencesen[56] Wang, B.; Huang, Q.; Venkitasamy, C.; Chai, H.; Gao, H.; Cheng, N.; Cao, W.; Lv, X.; Pan, Z. Changes in Phenolic Compounds and their Antioxidant Capacities in Jujube (Ziziphus jujuba Miller) during Three Edible Maturity Stages. LWT-Food Science and Technology 2016, 66, 56–62. https://doi.org/10.1016/j.lwt.2015.10.005
dc.relation.urihttp://dx.doi.org/10.1046/j.1440-6047.1999.00036.x
dc.relation.urihttps://doi.org/10.1186/cc3992
dc.relation.urihttps://doi.org/10.23939/chcht02.03.163
dc.relation.urihttps://doi.org/10.1042/bss0610073
dc.relation.urihttps://doi.org/10.23939/chcht16.04.591
dc.relation.urihttps://doi.org/10.23939/chcht05.01.013
dc.relation.urihttp://dx.doi.org/10.1111/j.1541-4337.2011.00156.x
dc.relation.urihttps://doi.org/10.1016/j.mrfmmm.2005.03.023
dc.relation.urihttps://doi.org/10.1016/s0278-6915(99)00090-3
dc.relation.urihttps://doi.org/10.1002/biof.1831
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2005.03.028
dc.relation.urihttps://doi.org/10.1093/ajcn/78.3.517S
dc.relation.urihttps://doi.org/10.1186/s12906-018-2285-7
dc.relation.urihttps://doi.org/10.1186/s13104-018-3960-y
dc.relation.urihttps://doi.org/10.4236/ajps.2018.96091
dc.relation.urihttps://doi.org/10.1038/nrd1657
dc.relation.urihttps://doi.org/10.1074/jbc.m305529200
dc.relation.urihttps://doi.org/10.3892/ijo.30.1.233
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2013.01.065
dc.relation.urihttps://doi.org/10.1002/cbdv.202200237
dc.relation.urihttp://dx.doi.org/10.21608/ejar.2011.179481
dc.relation.urihttps://doi.org/10.21162/PAKJAS/20.7845
dc.relation.urihttp://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).818-21
dc.relation.urihttps://doi.org/10.4314/tjpr.v6i2.14649
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2013.11.022
dc.relation.urihttps://doi.org/10.2202/1553-3840.1214
dc.relation.urihttps://doi.org/10.1007%2Fs10616-008-9131-6
dc.relation.urihttps://doi.org/10.1186/s40816-020-00246-0
dc.relation.urihttps://doi.org/10.1016/j.aoas.2022.12.003
dc.relation.urihttps://doi.org/10.1016/j.toxrep.2020.06.010
dc.relation.urihttps://doi.org/10.1080/10496475.2019.1600627
dc.relation.urihttps://doi.org/10.1016/j.psra.2016.09.001
dc.relation.urihttps://doi.org/10.38212/2224-6614.2748
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2006.09.025
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2012.11.001
dc.relation.urihttp://doi.org/10.1016/j.indcrop.2012.10.012
dc.relation.urihttps://doi.org/10.1021/jf026182t
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2007.04.038
dc.relation.urihttp://dx.doi.org/10.1590/S0101-20612014005000015
dc.relation.urihttps://doi.org/10.1038/s41598-022-06313-5
dc.relation.urihttps://doi.org/10.1111/j.1750-3841.2012.02946.x
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2016.01.090
dc.relation.urihttps://doi.org/10.1016/j.scienta.2011.06.005
dc.relation.urihttps://doi.org/10.1365/s10337-010-1485-1
dc.relation.urihttps://doi.org/10.1021/jf4007032
dc.relation.urihttps://doi.org/10.1371/journal.pone.0254058
dc.relation.urihttps://doi.org/10.1021/jf051513y
dc.relation.urihttps://doi.org/10.1002/pca.777
dc.relation.urihttps://doi.org/10.1016/j.foodchem.2008.04.068
dc.relation.urihttps://doi.org/10.1016/S0308-8146(99)00093-X
dc.relation.urihttps://doi.org/10.1023/a:1007078414639
dc.relation.urihttps://doi.org/10.23939/chcht17.02.397
dc.relation.urihttps://doi.org/10.1016/j.lwt.2015.10.005
dc.rights.holder© Національний університет “Львівська політехніка”, 2024
dc.rights.holder© Elhaty I., Zeyoudi S., 2024
dc.subjectZiziphus mauritiana
dc.subjectзизифус мавританський
dc.subjectантиоксиданти
dc.subjectаль-сидер
dc.subjectDPPH
dc.subjectОАЕ
dc.subjectZiziphus mauritiana
dc.subjectjujube
dc.subjectantioxidants
dc.subjectAl Sider
dc.subjectDPPH
dc.subjectUAE
dc.titleA Comparative Study of the Phenolic and Flavonoids Contents, and Antioxidant Activity of Ziziphus Mauritiana’s Leaves, Ripe and Unripe Fruit Extracts from UAE
dc.title.alternativeПорівняльне дослідження вмісту фенольних і флавоноїдних сполук та антиоксидантної активності екстрактів листя, стиглих і незрілих плодів Ziziphus mauritiana з ОАЕ
dc.typeArticle

Files

Original bundle

Now showing 1 - 2 of 2
Loading...
Thumbnail Image
Name:
2024v18n3_Elhaty_I_A-A_Comparative_Study_of_363-371.pdf
Size:
575.84 KB
Format:
Adobe Portable Document Format
Loading...
Thumbnail Image
Name:
2024v18n3_Elhaty_I_A-A_Comparative_Study_of_363-371__COVER.png
Size:
526.29 KB
Format:
Portable Network Graphics

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.76 KB
Format:
Plain Text
Description: